The full CIOC 2025 scientific program across 3 days — keynotes, oral presentations, and posters. Talks are ordered by program prominence within each day.
Day 1
- Keynote · In-Person
Molecular-genetic study of low-grade and high-grade “basal-like” (triple-negative) breast carcinomas
Farid Moinfar · Ordensklinikum Linz Barmherzige Schwestern, Austria
Introduction : Basal-like breast carcinomas are immunohistochemically positive for basal-type keratins such as K 5/6, K14, and K17 and mostly are triple-negative (negativity for ER, PR, and Her2/neu). “Basal-like” or…
- Keynote · In-Person
Altered expression of endoplasmic reticulum stress response genes and circular RNAs in oral squamous cell carcinoma tumorigenesis
Vandana Tiwari · Dr. Ram Manohar Lohia Institute of Medical Sciences, India
Background: Oral squamous cell carcinoma (OSCC) is a leading malignancy with high mortality and poor prognosis. Dysregulation of endoplasmic reticulum stress response (ERSR) genes and circular RNAs (circRNAs)…
- Oral · In-Person
Geospatial variation and assessment of factors with incidence of colorectal cancer at small area
Getachew Dagne · University of South Florida, United States
Background : Examining spatial distribution of colorectal cancer (CRC) incidence or mortality is helpful for developing cancer control and prevention programs, or for generating hypotheses. Such an investigation…
- Oral · In-Person
Flow cytometry for diagnosing malignant carcinomatous effusions
Namrata P Awasthi · Dr. Ram Manohar Lohia Institute of Medical Sciences, India
Background: The lecture will introduce the audience to commonly utilized techniques for Cytology of malignant fluids including cytospin, cell block and immunohistochemistry. The advantages and limitations of the…
- Oral · In-Person
Effectiveness of homoeopathic medicine for brochogenic carcinoma: A case report with pre & post HRCT report
Amir Ashraf · Dr. Amir’s Family Homoeopathy Clinic, India
Homoeopathy is an alternative system of medicine discovered by German physician Samuel Hahnemann in 1796. It has been used by several people for various health conditions globally for more than last 200 years. In India…
- Oral · In-Person
Genome-wide polymorphisms linked to treatment dosing and outcomes in Qatari pediatric acute lymphoblastic leukemia
Zainab Awada · Sidra Medicine, Qatar
Background : Childhood acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, yet significant inter-individual variability exists in response to its therapy. Genetic polymorphisms as biomarkers for…
- Oral · In-Person
The potential of Piper longum extract on breast cancer cell proliferation by inducing apoptosis
Shivam Singh · All India Institute of Medical Sciences, India
Background : The incidence of breast cancer has increased while the mortality rate has continued to remain high. Effective treatment of this disease is the key to survival. Therefore, this study is a necessity in…
- Oral · In-Person
Horizontal comparison of the trend of pancreatic cancer in China and abroad: Lower development correlates with reduced pancreatic cancer burden, defying SDI-based predictions
Yuxin Zhu · Nanchang University, China
Pancreatic cancer (PC), characterized by aggressive progression and poor prognosis, poses a critical global health challenge. This multinational study investigates epidemiological disparities in PC incidence and disease…
- Oral · In-Person
Unveiling gaps in cancer care: A qualitative study on the needs of patients from Northeast India
Redolen Rose Dhar · Manipal Academy of Higher Education, India
Background : Cancer is the leading cause of death worldwide, with the WHO projecting a 45% increase in global cancer deaths from 2008 to 2030 (1, 2). Beyond health impacts, cancer imposes significant economic strains…
- Oral · In-Person
Survivin and its splicing isoforms gene expression in oral squamous cell carcinoma patients
Phyu Ou Maung · University of Dental Medicine, Myanmar
Background: Oral squamous cell carcinoma (OSCC) has become a major oncologic problem. Survivin overexpression in OSCC could be associated with increased aggressiveness, poor response to chemotherapy and prediction of…
- Oral · In-Person
Decoding the universal proliferative engine of pituitary adenomas: From single-cell insights to cross-subtype therapeutic innovation
Changqin Pu · Peking Union Medical College Hospital, China
Objective: Pituitary adenomas (PAs) are clinically heterogeneous tumors with subtype-specific hormonal profiles, yet current therapies remain largely reactive and fail to address their proliferative core. This study…
- Oral · In-Person
Temozolomide treatment in refractory pituitary adenomas and pituitary carcinomas
Congcong Deng · Peking Union Medical College Hospital, China
Refractory pituitary adenomas (RPAs) and pituitary carcinomas (PCs) present significant therapeutic challenges, as they often do not respond to conventional treatment modalities such as surgery, radiation, and…
- Oral · In-Person
Cancer-associated fibroblasts derived soluble CADM1 predicts response to neoadjuvant chemoimmunotherapy in lung cancer
Jian Li · Shanghai Jiaotong University, China
Conventional neoadjuvant chemotherapy offers limited benefit for patients with resectable non-small-cell lung cancer (NSCLC). Recently, neoadjuvant chemoimmunotherapy (NCIT) has transformed perioperative management of…
- Oral · In-Person
Importin7 induces M2 macrophage and promotes the progress of colorectal cancer by regulating the nucleus translocation of GRP78
Changjiang Yang · Peking University People's Hospital, China
Recent research has linked Importin7 to cancer aggressiveness and a dismal prognosis, but its function in colorectal cancer (CRC) is unclear. This study aimed to elucidate the clinical relevance, biological function…
- Oral · In-Person
Community health workers role in advancing cervical cancer prevention and HPV vaccination in Mukono district, Uganda
Pauline Picho Keronyai · Nama Wellness Community Centre (NAWEC), Uganda
Cervical cancer remains a significant public health challenge in Africa, with the continent bearing approximately 19% of global cases. The East African region reports particularly concerning statistics, with an…
- Oral · In-Person
The prevention of post-ESD stricture of large early esophageal cancer by periodic triamcinolone injection
Li Mian Er · The Fourth Hospital of Hebei Medical University, China
Objective :Endoscopic submucosal dissection (ESD) is widely used for early esophageal cancer,but the post-ESD stricture rate of patients with a post-ESD mucosal defect of ≥ 3/4 of the esophageal circumference is…
- Poster · In-Person
BATF upregulates RGS2 expression to promote T cell exhaustion in lung cancer by activating the NF-kB pathway
Chanchan Gao · Zhongda Hospital, Southeast University, China
Objective: This study aimed to investigate the role of RGS2 in immune regulation and its impact on the efficacy of PD-1/PD-L1 blockade therapy in lung cancer (LC), as well as to explore the regulatory relationship…
- Poster · In-Person
Advancing cancer care: The impact of MYCNOS-SE on chemoresistance in SCLC
Yuchun Niu · Oncology Hospital of the First People's Hospital of Foshan, China
Understanding the Role of Super-enhancer MYCNOS-SE in Chemoresistance of Small Cell Lung Cancer. Small cell lung cancer (SCLC) is a highly aggressive malignancy characterized by rapid progression and a high propensity…
- Poster · In-Person
ADGRE+ CD8+ T cells overcome resistance to neoadjuvant immunotherapy in lung cancer
Jian Li · Shanghai Jiaotong University, China
Neoadjuvant immunotherapy with anti-programmed death-1 (neo-antiPD1) has revolutionized perioperative treatment for improving the overall survival (OS) of patients with early-stage lung cancer. Despite its…
Day 2
- Keynote · Virtual
Principles of oral rehabilitation in H&N cancer patients
Pietro Salvatori · Formerly, Humanitas San Pio X Hospital, Italy
Treatment goals for Head & Neck cancers can be indicated as: 1) Eradication of the tumor (ablative surgery or XRT, combinations), 2) Restoration of the anatomy (reconstructive surgery), 3) Rehabilitation of the…
- Keynote · Virtual
The future of pharmacogenetic polymorphism, pharmacogenomics and pharmamicrobiome in cancer treatment
Bene Ekine-Afolabi · University of East London, United Kingdom
Drug metabolism is crucial in any functioning of a drug, particularly in drugs for cancer treatment. Several drugs do not function in human body in their original state unless metabolised to its required functioning…
- Keynote · Virtual
Successful tumor growth control using PLGA nanoparticles loaded with selol and nanomaghemite
Paulo Cesar De Morais · Catholic University of Brasilia, Brazil
Poly(lactic-co-glycolic acid) (PLGA) nanoparticle has proven extremely useful for drug delivery, thanks to its high biocompatibility, biodegradability, and toxicologically safe degradation products. This talk will…
- Keynote · Virtual
Biosensor-based detection of cancer biomarkers
Michael Thompson · University of Toronto, Canada
Biosensor technology represents an attractive strategy for the detection and monitoring of biomarkers for disease states within the context of precision medicine. This approach offers the possibility for biomarker assay…
- Keynote · Virtual
A novel mRNA genomic technology for precision medicine, early cancer diagnosis, prognosis, treatment follow-up and cancer gene therapy
Rajvir Dahiya · University of California San Francisco, United States
Background : Current screening methods, have limitations in the diagnosis and prognosis of prostate cancer. This study examined whether mRNA-genomic biomarkers can improve screening and monitoring of prostate cancer.…
- Oral · Virtual
Protein structure maintenance, intracellular signaling and tumor suppression contributed by zinc finger protein ZMYND10
Xiangning Zhang · Guangdong Medical University, China
On short arm of human chromosome 3, a region 3p21, which is deleted in a variety of tumors, harbors a cluster of putative tumor suppressor genes (TSGs). One of the TSG candidates, BLU, coding for a zinc protein ZMYND10…
- Oral · Virtual
Histone lactylation drives oncogenesis and function as a prognostic marker in pancreatic ductal adenocarcinoma
Wenzhe Si · Peking University Third Hospital, China
Background: Metabolic reprogramming and epigenetic alterations contribute to the aggressiveness of pancreatic ductal adenocarcinoma (PDAC). Lactate-dependent histone modification is a new type of histone mark, which…
- Oral · Virtual
Autophagy as an immunomodulatory signalosome in toll-like receptors/Wnt-Frizzled mediated inflammatory “gastrohepatic disease-web” in hepatocellular/colorectal/cholangio-carcinomas: Translational research and public health impact in American cohorts of Texas, Nebraska and New York states in USA
Saumya Pandey · Indira IVF Hospital, India
Objective : Dissecting the cellular/molecular/genetic regulatory biochemical signaling networks: Autophagy/Toll-like Receptors/Wnt-Frizzled in inflammatory “gastrohepatic disease-web” primarily…
- Oral · Virtual
Bioscope: A new instrumental approach for early diagnosis of oncological diseases
Luiza Simonyan · L. Orbeli Institute of Physiology of the National Academy of Sciences of Armenia, Armenia
Modern medical methods of treatment allow in some cases to prevent the development of pathological processes in the human body. It is known that the effectiveness of such therapeutic effects is largely determined by the…
- Oral · Virtual
Association between respiratory tract viral PCR panel results and clinical outcomes in children with cancer and febrile neutropenia
Özlem Terzi · Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Turkey
Febrile neutropenia (FEN) is the most common life-threatening complication of childhood cancer. Early initiation of broad-spectrum intravenous antibiotics to patients has reduced the mortality of FEN below 5%. Studies…
- Oral · Virtual
Colorectal cancer and associated risk factors: Case control hospital based study in Egypt
Ibrahim El Bayoumy · Consultant of Public Health-Ministry of Health, Kuwait
Background Colorectal cancer accounts for approximately 10% of all annually diagnosed cancers and cancer-related deaths worldwide.1 It is the second most common cancer diagnosed in women and third most in men. In women…
- Oral · Virtual
Breaking the silence: Breast cancer extracellular vesicles as key players in breast cancer immune suppression
Nayara Delgado André Bortoleto · Federal University of Sao Joao del Rei, Brazil
Breast cancer is the most prevalent malignancy in women worldwide and remains a leading cause of cancer-related mortality. Immune system controls tumor progression but is often suppressed in breast cancer. Dendritic…
- Oral · Virtual
Developing a digital decision-support tool for personalized treatment of metastatic thyroid cancer
Marie Fusella Giuntini · University of Corsica, France
Each year, a high number of new cases of thyroid cancer are identified. Although this disease has a good prognosis, it is often immediately metastatic, which requires removal of the thyroid body, followed by iratherapy…
- Oral · Virtual
A new tension-sensitive signaling pathway involving polymerization of actin prevents chromatin bridge breakage in cytokinesis
Eleni Petsalaki · University of Crete, Greece
Chromatin bridges are strands of incompletely segregated DNA connecting the anaphase poles or daughter nuclei. Chromatin bridges can arise from incompletely replicated DNA, defective resolution of DNA catenates or…
- Oral · Virtual
Associated factors to practice of breast cancer screening among women in Parakou at 2021
Maurice T. Agonnoude · Parakou University, Benin
Introduction: The integration of breast cancer screening into daily clinical care leads to an early diagnosis and reduces its mortality. However, many women are reluctant and do not get tested. Objective To study the…
- Oral · Virtual
Bioinformatics and genomic approaches for assessing gene fusion process in MCF7 breast cancer cell models under early estradiol stimulation for assessing estrogen receptor β (Erβ) tumor suppressor activity
Dago Dougba Noel · PELEFORO GON COULIBALY University, Côte d'Ivoire
Cancers are genetic and epigenetic diseases in which cells divide and grow in uncontrolled ways due to mutations or molecular alterations. Gene fusion phenomena is recurrent in cancer cells. One of the most common…
- Poster · Virtual
Laparoscopic-endoscopic cooperative non-exposed wall-inversion surgery combined with sentinel node navigation surgery in the treatment of early gastric cancer: A multicenter retrospective study
Shuaiqi Wang · Chongqing University Cancer Hospital, China
Background : We developed the laparoscopic and endoscopic cooperative surgery (LECS) technique, which combines non-exposed wall-inversion surgery (NEWS) and sentinel node navigation surgery (SNNS) to treat early gastric…
- Poster · Virtual
Laparoscopic-endoscopic cooperative non-exposed wall-inversion surgery combined with sentinel node navigation surgery in treatment of early gastric cancer: A multicenter retrospective study
Hao Sun · Chongqing University Cancer Hospital, China
Background : We developed the laparoscopic and endoscopic cooperative surgery (LECS) technique, which combines non-exposed wall-inversion surgery (NEWS) and sentinel node navigation surgery (SNNS) to treat early gastric…
- Poster · Virtual
Development of risk stratification tool to appropriately triage the patients at risk of recurrence in HR+ HER2- early breast cancer
Somashekhar SP · Aster CMI Hospital, India
Introduction: HR+/HER2-negative Early Breast Cancer (EBC) is treated with curative intent, but managing locoregional and distant recurrences remains a significant challenge. The lack of a standard risk-identification…
Day 3
- Keynote · Virtual
The role of artificial intelligence (AI) in oncology
Marika Crohns · Impactful Innovations Management Consultants LLC, United Arab Emirates
Artificial Intelligence (AI) has emerged as a transformative force in oncology, offering unparalleled potential to revolutionize cancer care. By leveraging advanced algorithms and machine learning models, AI enhances…
- Keynote · Virtual
Targeting noncanonical epitopes in anti-cancer immunotherapy
Michele Mishto · Francis Crick Institute, United Kingdom
MHC class I complexes can present antigenic peptides that have a sequence produced by post-translational mechanisms such as peptide splicing. Some examples of tumour-associated spliced epitopes have been investigated…
- Keynote · Virtual
Updates on cancer research for detection and management
Patricia Tai · University of Saskatchewan, Canada
About 2 in 5 Canadians are expected to be diagnosed with cancer in their lifetime and 1 in 4 die of it. I would discuss interesting updates of advances in cancer research. Biomarker assays have become routine for some…
- Keynote · Virtual
RNA binding proteins in the pathogenesis of pediatric cancer
Atif A Ahmed · Seattle Children’s Hospital, United States
RNA binding proteins (RBPs) are regulators of RNA metabolism and influence protein expression in various physiologic and pathologic conditions through regulation of RNA splicing, stability and translation. Several…
- Keynote · Virtual
Theory and perspective: How big data and AI accelerate the discovery of a universal cancer principle from the noncoding RNA regime
Anyou Wang · DIFIBER LLC, United States
Numerous cancer-related mechanisms are reported daily, yet a universal theory for eradicating all cancers remains elusive. Fortunately, recent advances in big data and AI have identified noncoding RNAs as central…
- Oral · Virtual
Application of magnetic resonance-diffusion weighted imaging in thyroid nodules
Liling Jiang · Shapingba District People's Hospital of Chongqing, China
All studies were performed on a 3 T whole-body MRI system (MAGNETOM Prisma, Siemens Healthineers, Erlangen, Germany) using a 16-channel surface coil (Zhongzhi Medical, Jiangsu). Firstly, we evaluated the thyroid nodule…
- Oral · Virtual
Overcoming drug resistance to BET inhibitors by rational combinative strategies
Jiawei Guo · Sichuan University, China
Bromodomain and extra-terminal (BET) family members, including BRD2, BRD3, BRD4 and BRDT, function as critical readers of acetylated histones and globally activate oncogene expression. These proteins have emerged as…
- Oral · Virtual
Evaluation of mutational values in cancerous point mutation and innovation of values-effective drugs for cancer treatment
Ratan Kumar Sarkar · Independent Researcher, India
The molecular weights of amino acids are time values where integer and decimal part have separate identity but interrelated. Derived from the factor 14.0267 e.g. 119.1197(Thr) – 105.0930(Ser) = 14.0267 = 131.1736(Leu)…
- Oral · Virtual
Efficient anticancer properties of ashwagandha extracted phytochemicals for lower protein expression on U-251 and clove extracts on LN-229 GBM cell lines
Prabha Muddobalaiah · Ramaiah Institute of Technology, India
Glioblastoma Multiforme G IV primary malignant Brain tumor medications such as Radiation, Surgery, Gene therapy, Chemotherapy and Ayurveda which are not very much successful with clinical studies. However, the trials…
- Oral · Virtual
Behavior of advanced (T3 & T4) squamous cell carcinoma of the oral cavity
Gaurav Vishal · Prathima Cancer Institute, India
Squamous cell carcinoma (SCC) is the most common malignant neoplasm of the oral cavity. SCC is a major health problem for the world. Based on GLOBOCAN estimates, about 377,713 new cancer patients and 177,757 deaths…
- Oral · Virtual
The next generation cancer treatments - the role of genomics and AI
K R Muralidhar · Karkinos Healthcare Private Limited, India
The discussion will be on optimum utilization of AI and genomics in delivering personalized treatments inRadiationOncology for better treatment outcome. Artificial Intellignce , Machine learing and Deep learning will…
- Oral · Virtual
Oxidative stress–fighting miRNAs: Targeting cancer’s achilles’ heel
Sinem Durmus · Izmir Katip Celebi University, Turkey
Oxidative stress is one of major factors of cancer initiation and progression by inducing damage to cellular macromolecules through the accumulation of reactive oxygen species (ROS). This process contributes to tumor…
- Oral
Development and validation of an inflammatory prognostic index to predict outcomes in advanced/metastatic urothelial cancer patients receiving immune checkpoint inhibitors
Sara Mokbel · University College London, United Kingdom
Background : Immune checkpoint inhibitors (ICIs) improve overall survival (OS) in advanced/metastatic urothelial cancer (a/mUC) patients. Preliminary evidence suggests a prognostic role of inflammatory biomarkers in…
- Oral · Virtual
System error in cancer research
Oleg Bukhtoyarov · Medical Center 39 LLC, Russian Federation
Undoubtedly, cancer refers to the group called “diseases of civilization”. Over the last 100 years, cancer has become a real nightmare for humanity. Despite having the tremendous world scientific and financial…
- Oral · Virtual
Synthesis and characterization of ruthenium(III) complex containing 2-aminomethyl benzimidazole, and its anticancer activity in in vitro and in vivo models
Abdel Ghany F. Shoair · Damietta University, Egypt
A novel ruthenium(III) complex with 2-aminomethyl benzimidazole (AMBI) has been synthesized and characterized by elemental analysis, spectroscopic (FTIR, UV–Vis and XRD), thermal, magnetic and electrochemical…
- Oral · Virtual
Effect of BRCA silence on the nervous system in a murine model of breast cancer
Andrea González Báez · Autonomous University of Nuevo Leon, Mexico
Cancer is a complex pathology of great relevance for public health due to its high mortality and morbidity. Specifically breast cancer, is one of the main causes of death in women worldwide, demonstrating that its…
- Oral · Virtual
Superficial radiation ulcer of the skin: Comparison of the innovative photodynamic therapy (used in the first documented Canadian case) with other alternatives
Patricia Tai · University of Saskatchewan, Canada
Introduction : Photodynamic therapy (PDT) promotes wound healing while its clinical use is not investigated in human for radiation-induced skin ulcers. Methods and Materials : We documented the first Canadian in-human…
- Oral · Virtual
Proposal for new diagnostic criteria for sarcopenia based on CT imaging in the Saudi population: A novel method in oncology research
Zahra Husain · Government Hospital, Bahrain
Background: Sarcopenia has been shown to be an independent predictor of lower overall survival in oncology patients. Several studies have used computed tomography (CT) to measure psoas muscle surface area to define…
- Oral · Virtual
MicroRNA expression analyses reveal biomarker candidates for improved diagnosis and prognosis of pediatric Burkitt lymphoma
Can Küçük · Dokuz Eylul University, Turkey
Burkitt lymphoma is the most common non-Hodgkin lymphoma in children. Pediatric Burkitt lymphomas (pBLs) are characterized by fast tumor growth; therefore, rapid diagnosis and initiation of therapy is of utmost…
Present your research at CIOC 2027
Abstract submissions for the 2027 program are open · March 15–17, 2027 · Village Hotel Changi, Singapore.
Join the CIOC 2027 delegation
Singapore · March 15–17, 2027· Hybrid · in-person & virtual
Attend without presenting.