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2nd Edition of International Cancer Research Conference

March 19-21, 2026 | Singapore

March 19 -21, 2026 | Singapore
Cancer Research 2025

Evaluation of mutational values in cancerous point mutation and innovation of values-effective drugs for cancer treatment

Speaker at International Cancer Research Conference 2025 - Ratan Kumar Sarkar
Independent Researcher, India
Title : Evaluation of mutational values in cancerous point mutation and innovation of values-effective drugs for cancer treatment

Abstract:

The molecular weights of amino acids are time values where integer and decimal part have separate identity but interrelated. Derived from the factor 14.0267 e.g. 119.1197(Thr) – 105.0930(Ser) = 14.0267 = 131.1736(Leu) – 117.1469(Val), the formula T(time) = 0.0019*M(integer) is important with a difference of 0.0001 or 1 associated with directional biology. The values 0.0267 = 0.0154 + 0.0113(6) are factors of opposite since 0.1605 – 0.1451 = 0.0154 and 777(183) – 771(i.e. 357 + 414) = 6 and conversely 177 + 6 = 183(lunar time). To evaluate mutational values, the core values(Cv) of amino acid have to be measured e.g. 181.1894(Tyr) = 181*0.0019 – 0.1894 = 0.1545 or 645(under suppression) = 900 – 255. The biophysical structure or electro-gravitational structure works within 900 and the reverse domain 109 and Tyr-Val chemistry constitutes an electro-gravitational structure where 289 + 136 = 425 = 938 – 513(27) and also Tyr-Met chemistry constitutes an electro-gravitational structure where 519 + 289 = 808 and conversely 519 – 289 = 230 where 808 – 230 = 578 = 575 + 3. The values are measured from lunar gravity(0.1605 or 705) with decimal part where 0.2124(Met) – 0.1605 = 0.0519 or 519, 0.1894(Tyr) – 0.1605 = 0.0289 or 289 and  0.1605 – 0.1469(Val) = 0.0136 or136. The electro-gravitational structure is based on 0.3477(183) – 0.2902(i.e.0.1451*2) = 0.0575 or 575 = 0.1605 – 0.1031(i.e. 900 – 131= 769 that reverse of 967 where 193*0.0019 = 0.3667 or 967) where 0.1451 = 0.0938 + 0.0513. The molar masses of proton 938.28 Mev/C2 and that of electron 0.511Mev/C2 with a significant 0.0002 time difference. The electro-gravitational structure activates if there is a difference of 100 towards structural mutation or blocking of time by ‘9’(0.0171 or 171) where 289 shows tyrosine kinase activity due to blocking of time in directional biology and 28*82 = 2296 or 496 where 575 + 496 = 1071 or 171 and conversely 496 – 325 = 171 in 900 = 575 + 325 and if 575 is positive then 325 runs negative. There are some crucial structure, 900 = 360 + 540 = 289 + 611 = 645 + 255 = 513 + 387 in the system where the intermediate values 645 – 255 = 390 is associated with 109 where 390 + 109 = 499(reverse of 994) and 289 – 255 = 34(i.e. 0.0646) is significant. The JAK2 G1849T V617F and TP53 G469T V157F would be standard manifestation where core values of Val = 754 = 900 -146(complementary values of 469 point) and 705 + 49(beyond 900) = 754 and 109 + 49 = 158. The Val754 can be a pathfinder for drug assessment. The EGFR lung cancer mutations L858R, C797S and T790M are interrelated where 858 + 797 = 1655 or 755 and 858 – 109 = 749 and 797 – 109*2 = 579 are the causes of cancer since time is indomitable and cannot be stopped. It is found 790 – 540 = 250 = 575 – 325 where 360 – 250 = 110(suppressed). In BRAF V600E, 754 – 600 = 154 and 600 – 6 = 594(E) where 154 + 6 = 160 causes cancer.

Biography:

Ratan Kumar Sarkar graduated with a B.Sc. from the University of Calcutta and has published over twenty research papers in Scientific and Academic Publishing journals. He also participated in the International Cancer Research Conference 2025, contributing to global discussions on cutting-edge developments in cancer research.

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