Background: Current screening methods, have limitations in the diagnosis and prognosis of prostate cancer. This study examined whether mRNA-genomic biomarkers can improve screening and monitoring of prostate cancer. Methods: We identified a panel of 25 prostate cancer-related [....] » Read More
Drug metabolism is crucial in any functioning of a drug, particularly in drugs for cancer treatment. Several drugs do not function in human body in their original state unless metabolised to its required functioning metabolite to affect its target organ/site or tissue. Drug metab [....] » Read More
Biosensor technology represents an attractive strategy for the detection and monitoring of biomarkers for disease states within the context of precision medicine. This approach offers the possibility for biomarker assay via incorporation into an automated robotic system to proces [....] » Read More
Cancer is a complex pathology of great relevance for public health due to its high mortality and morbidity. Specifically breast cancer, is one of the main causes of death in women worldwide, demonstrating that its incidence has been exponentially uprising. The multifactorial natu [....] » Read More
Autophagy exerts a vital role in lung squamous cell carcinoma (LUSC) progression. Ubiquitin Specific Peptidase 31 (USP31) has recently been found to be involved in the development of a variety of cancers. However, whether USP31 modulates autophagy in LUSC remains uncovered. This [....] » Read More
My topic focus on precision medicine and translational research of breast cancer, including three parts: 1. Homologous recombination repair deficiency in breast cancer; 2. Clinical patterns and predictive models of cancer metastasis; 3. Tumor immunity and the immune microenvironm [....] » Read More
All studies were performed on a 3 T whole-body MRI system (MAGNETOM Prisma, Siemens Healthineers, Erlangen, Germany) using a 16-channel surface coil (Zhongzhi Medical, Jiangsu). Firstly, we evaluated the thyroid nodule image quality between two diffusion weighted imaging (DWI) te [....] » Read More
Introduction: Worldwide, breast cancer comprises one third of all cancers affecting women. Disparities are exhibited by this condition in tumor biology and clinical behavior. No single cure has been identified as a result of these characteristics. Scientists all around the globe, [....] » Read More
This study introduces a novel thermodynamic marker for cancer diagnosis, revealing a fundamental interrelationship between membrane tension, the aspect ratio of cells during late anaphase, and spindle angle. Central to this discovery is the identification of Inter-Cyto-Tension (I [....] » Read More
Neuroendocrine tumours (NETs) of the gallbladder are rare and represent a challenging clinical scenario due to their aggressive nature and late presentation. We report a case of a 60-year-old female diagnosed with a stage 4B neuroendocrine tumour of the gallbladder. This case und [....] » Read More
Introduction: The integration of breast cancer screening into daily clinical care leads to an early diagnosis and reduces its mortality. However, many women are reluctant and do not get tested. Objective To study the factors associated with the practice of breast cancer scre [....] » Read More
Modern medical methods of treatment allow in some cases to prevent the development of pathological processes in the human body. It is known that the effectiveness of such therapeutic effects is largely determined by the possibility of diagnosing the disease at the initial stages [....] » Read More
Background: We developed the laparoscopic and endoscopic cooperative surgery (LECS) technique, which combines non-exposed wall-inversion surgery (NEWS) and sentinel node navigation surgery (SNNS) to treat early gastric cancer (EGC). It is a technique which preserves organ functio [....] » Read More
Title : Hospital care for cancer patients - safety, quality of care, education and respect for patient’s rights
Mariola Wioletta Borowska, Maria Sklodowska-Curie National Research Institute of Oncology, Poland
Hospital care quality and communication with cancer patients is a critical issue in the treatment of this kind of patient. As a chronic, complex illness, cancer treatments and communications with cancer patients need to be more than just providing information. Communication betwe [....] » Read More
Title : Importin7 induces M2 macrophage and promotes the progress of colorectal cancer by regulating the nucleus translocation of GRP78
Changjiang Yang, Peking University People's Hospital, China
Recent research has linked Importin7 to cancer aggressiveness and a dismal prognosis, but its function in colorectal cancer (CRC) is unclear. This study aimed to elucidate the clinical relevance, biological function, and potential molecular mechanisms of IPO7 in CRC. Our results [....] » Read More
Title : Cancer-associated fibroblasts derived soluble CADM1 predicts response to neoadjuvant chemoimmunotherapy in lung cancer
Jian Li, Shanghai Jiaotong University, China
Conventional neoadjuvant chemotherapy offers limited benefit for patients with resectable non-small-cell lung cancer (NSCLC). Recently, neoadjuvant chemoimmunotherapy (NCIT) has transformed perioperative management of NSCLC by priming systemic anti-tumor immunity before surgery, [....] » Read More
Title : Flow cytometry for diagnosing malignant carcinomatous effusions
Namrata P Awasthi, Dr. Ram Manohar Lohia Institute of Medical Sciences, India
Background: The lecture will introduce the audience to commonly utilized techniques for Cytology of malignant fluids including cytospin, cell block and immunohistochemistry. The advantages and limitations of the techniques will be discussed. Further, basics of flow cytometry (FCM [....] » Read More
Title : Chalepin suppresses cell growth by down-regulation of the epidermal growth factor receptor downstream pathways and induced cell cycle arrest in MCF7 breast cancer cells
Isah Musa Fakai, Kebbi State University of Science and Technology, Nigeria
The epidermal growth factor receptor (EGFR) pathway is an important signaling cascade currently investigated for its involvement in cancer therapy. In this study, chalepin isolated from Ruta angustifolia was evaluated for its down regulatory activity on the EGFR signaling cascade [....] » Read More
Title : HPV vaccination coverage in the European region
Mariola Wioletta Borowska, Maria Sklodowska-Curie National Research Institute of Oncology, Poland
The human papillomavirus (HPV) is an established cause of cervical cancer and other HPV-related diseases. This study aims to analyze the variation in coverage by HPV vaccination programs – particularly within European Region countries – and explore possible healt [....] » Read More
Title : Implementation of a population-based breast cancer prevention program in Poland before, during and after the COVID-19 pandemic. Poland in comparison with other countries
Mariola Wioletta Borowska, Maria Sklodowska-Curie National Research Institute of Oncology, Poland
Breast cancer is the most common malignant tumor in women in Poland and in the world. It accounts for about 24% of all cancer cases in Polish women. According to the latest report published in November 2022 by the Sarcoma Association for Sarcomas and Melanomas, as many as 39% of [....] » Read More
Title : Understanding the role of super enhancer MYCNOS-SE in chemoresistance of small cell lung cancer
Niu Yuchun, Oncology Hospital of the First People's Hospital of Foshan, China
Understanding the Role of Super-enhancer MYCNOS-SE in Chemoresistance of Small Cell Lung Cancer. Small cell lung cancer (SCLC) is a highly aggressive malignancy characterized by rapid progression and a high propensity for chemotherapy resistance. This presentation will discuss [....] » Read More
Title : ADGRE5+ CD8+ T cells overcome resistance to neoadjuvant immunotherapy in lung cancer
Jian Li, Shanghai Jiaotong University, China
Neoadjuvant immunotherapy with anti-programmed death-1 (neo-antiPD1) has revolutionized perioperative treatment for improving the overall survival (OS) of patients with early-stage lung cancer. Despite its transformative impact, neo-antiPD1 provides limited benefit to nearly 50% [....] » Read More
Title : The impact of social marketing based intervention on educating esophageal cancer preventive behaviors
Davoud Shojaeizadeh, Tehran University of Medical Sciences, Iran (Islamic Republic of)
Esophageal cancer is one of the most widespread disease in Golestan Province , Iran. To identify risk factors a lot of research has been done. Because health workers have successful experiences of health education. The purpose of this study is to use social marketing to influence [....] » Read More
Title : Euxanthone suppresses the proliferation of human hepatocellular carcinoma cells via miR-199a-5p/E2F3 axis
Ahmed Al Awadh, Najran University, Saudi Arabia
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. This study aimed to evaluate the effects of euxanthone on the proliferation and migration of HCC cell lines and elucidate the underlying molecular mechanisms. Methods: HCC cell [....] » Read More
Title : Study of the participatory communication on good territorial governance performance in Tantan city, Morocco
Hefdhallah Al-Aizari, Ibn Tofail University, Morocco
Participatory and collaborative communication plays a crucial role in territorial governance to find innovative solutions for the proper functioning of public service. This study examines the importance of participatory and collaborative communication in good territorial governan [....] » Read More