The full CIOC 2026 scientific program across 3 days — keynotes, oral presentations, and posters. Talks are ordered by program prominence within each day.
Day 1
- Keynote · In-Person
Personalized and Precision Medicine (PPM) through the view of biodesign-inspired translational research: An option for clinical oncologists, caregivers, and consumers to realize the potential of genomics-informed care to secure human biosafety
Sergey Suchkov · N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized and precision medicine (PPM). Meanwhile, the era of genomics-based medicine and thus…
- Keynote · In-Person
Updates on controversies surrounding the staging and management of newly diagnosed localized prostate cancer using Prostate-Specific Membrane Antigen (PSMA) positron emission tomography
Patricia Tai · University of Saskatchewan, Canada
Prostate cancer is a very common malignancy in men, particularly in the Western world, although its incidence is lower among Asians. It can be identified using the relatively new prostate-specific membrane antigen…
- Oral · In-Person
tRNA-derived fragment 3'tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan · The Affiliated Cancer Hospital of Nanjing Medical University, China
Background Drug resistance, including Adriamycin-based therapeutic resistance, remains a challenge in breast cancer (BC) treatment. Studies have revealed that macrophages could play a pivotal role in mediating the…
- Oral · In-Person
Discovery of an R-spondin–ALK–Wnt axis: Expanding the oncogenic landscape of anaplastic lymphoma kinase
Chockalingam S · National Institute of Technology Warangal, India
Anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase, has emerged as a critical driver of malignancy in diverse cancers such as anaplastic large cell lymphoma, non-small cell lung cancer, and neuroblastoma.…
- Oral · In-Person
A case-based approach using IMPeTUs criteria in FDG PET/CT reporting of multiple myeloma
Mudalsha Ravina · All India Institute of Medical Sciences, India
[18F]FDG PET/CT has become an integral component in the evaluation of Multiple Myeloma (MM), offering significant advantages in disease detection, staging, treatment response assessment, and prognostication. The Italian…
- Oral · In-Person
A pioneering, first-of-its-kind Canadian off-site program designed to reduce the burden on hospital staff and optimize the use of space
Patricia Tai · University of Saskatchewan, Canada
Aim : Degarelix, a GnRH antagonist for ADT, showed remarkable results in clinical trials. We launched Canada’s first off-site injection program to decentralize services from overloaded acute care settings. This is the…
- Oral · In-Person
A prospective study of tislelizumab combined with radiotherapy in unresectable or recurrent advanced hepatocellular carcinoma: Efficacy and immunological safety analysis
Han Sun · Liaoning Cancer Hospital & Institute, China
Background: Radiotherapy (RT) can induce immunogenic cell death and enhance tumor antigen release and presentation, thereby augmenting the host anti-tumor immune response. The combination of PD-1 inhibitor tislelizumab…
- Oral · In-Person
Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye · Guangxi Medical University Cancer Hospital, China
In this study we are the first worldwide to reveal a GP73-mediated regulatory network that promotes tumor angiogenesis and progression in Hepatocellular carcinoma (HCC) under hyperxia stress. Our findings demonstrated…
- Oral · In-Person
Phosphate analog PPF inhibits papillary thyroid cancer by disrupting phosphate balance and reprogramming tumor metabolism
Yuanhao Su · Second Affiliated Hospital of Xi'an Jiaotong University, China
Background : The global incidence of papillary thyroid cancer (PTC) has been increasing in recent years, placing greater demands on healthcare systems worldwide. While standard treatments such as surgery combined with…
- Oral · In-Person
Development and validation of a clinical decision-support model for preoperative individualized assessment of high-volume central lymph node metastasis in older adults (over 55 years) with papillary thyroid carcinoma
Yongke Wu · The Second Affiliated Hospital of Xi’an Jiaotong University, China
Background : Elderly patients with papillary thyroid carcinoma (PTC) constitute a unique subgroup in clinical practice, often exhibiting more aggressive tumor characteristics. Although current guidelines offer few…
- Oral · In-Person
Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng · Tianjin Medical University Cancer Institute and Hospital, China
Chemoresistance remains the predominant cause of treatment failure in osteosarcoma (OS), yet its underlying molecular circuitry remains poorly defined. To address this gap, we conducted a series of mechanistic and…
- Oral · In-Person
Bevacizumab versus anlotinib respectively combined with chemotherapy drug in the treatment of EGFR-TKI acquired resistant advanced lung adenocarcinoma
Yanyu Qi · Chengdu Third People's Hospital, China
Objective: To compare the short-term therapeutic efficacy and safety of bevacizumab versus anlotinib, each in combination with chemotherapy, for the treatment of advanced lung adenocarcinoma with acquired resistance to…
- Oral · In-Person
Evaluation of survival prognostic factors in different treatment modalities for locally advanced unresectable esophageal squamous cell carcinoma
Yanni Zhang · Liaoning Cancer Hospital & Institute, China
Background: Esophageal cancer, particularly esophageal squamous cell carcinoma (ESCC), remains a leading cause of cancer-related mortality worldwide. This study investigates the impact of different treatment modalities…
- Oral · In-Person
Intraocular lymphomas associated with primary CNS lymphomas: Great mystification. Clinical landscape and diagnostic challenges
Maria S Shmelkova · Burdenko National Research Neurosurgery Center, Russian Federation
Primary intraocular lymphomas (PIOL) or vitreoretinal lymphomas (VRL) are a type of primary central nervous system lymphoma (PCNSL), accounting for approximately 2–3% of all non-Hodgkin lymphomas and developing in about…
- Oral · In-Person
Personalized and precision oncology via integrating genomics, pathology-related modeling, and IT-assisted approaches to prevent, treat, and cure cancer and its complications
Sergey Suchkov · N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Individualizing patient treatment is a core objective of the medical field. Meanwhile, the inherent variability of cancer illustrating the molecular differences between tumors, securing the linkages of those differences…
- Oral · In-Person
Pleural fluid C-C motif chemokine ligand 2: An effective biomarker for diagnosing malignant pleural effusion
Li Ma · Beijing Chest Hospital, China
Background : Accurate diagnosis of malignant pleural effusion (MPE) using biomarkers remains challenging. C-C motif chemokine ligand 2 (CCL2), a chemokine markedly overexpressed under pathological conditions, has…
- Oral · In-Person
Programmable enzyme–enabled ultra-sensitive liquid biopsy for early detection of tumor MRD
Jinzhao Song · Hangzhou Institute of Medicine, Chinese Academy of Sciences, China
Minimal residual disease (MRD) can persist in cancer patients even after potential cure, resulting in cancer recurrence and contributing to the low five-year survival rate of cancer patients. Currently, circulating…
- Oral · In-Person
BCL2A1 expression in CD8+ T cells is associated with survival and immune checkpoint blockade response in lung adenocarcinoma
Hoang Minh Quan Pham · Taipei Medical University, Taiwan
Background: Biomarkers associated with response to immune checkpoint blockade (ICB) in lung adenocarcinoma (LUAD) remain incompletely defined. This study examined the transcriptional landscape of BCL2A1 in CD8? T cells…
- Oral · In-Person
Unmasking the cytokine storm: A spectrum of paediatric hemophagocytic lymphohistiocytosis across immuno-oncologic, infectious, and genetic landscapes - insights from a tertiary oncology centre in South India
Megadeepan Senthilkumar · Kidwai Memorial Institute of Oncology, India
Background : Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome with heterogeneous triggers, ranging from genetic predispositions and immunodeficiencies to malignancies and infections. We report…
- Poster · In-Person
Targeting HSD11B2–PD-L1 axis: A novel strategy to reverse immune escape and spontaneous metastasis in renal cell carcinoma
He Haowei · Jinling Hospital, China
Background: Metastatic renal cell carcinoma (mRCC) remains a therapeutic challenge with poor prognosis, as current immunotherapy combinations often encounter resistance. Immune escape is a key driver of spontaneous…
- Poster · In-Person
Identification of prognostic biomarkers and potential therapeutic targets for lung cancer by metabolomics analysis
Li Su · Harvard T.H. Chan School of Public Health, United States
Rationale: Metabolic reprogramming is a hallmark of lung cancer and a source of druggable vulnerabilities. Bridging mechanistic metabolic signatures with clinical prognostication may reveal targetable pathways that…
- Poster · In-Person
The oncogenic role of KCNN4 in renal clear cell carcinoma: A mechanism involving immune regulation via Tregs and resting mast cells
Xiaoming Yi · Jinling Hospital, China
Background: Renal cell carcinoma (RCC) is a common malignant tumor of the urinary system, with clear cell RCC (ccRCC) representing its predominant subtype. The pathogenesis of ccRCC remains incompletely understood.…
- Poster · In-Person
Phytohormone strigolactams overcome oxaliplatin resistance in colorectal cancer by blocking late-stage autophagy to tip the metabolic balance toward ferroptosis
Xingyue Chen · Southeast University, China
My presentation addresses one of the most pressing challenges in oncology: Treatment Resistance. I will focus on a novel strategy to overcome oxaliplatin resistance in colorectal cancer, titled " Phytohormone…
- Poster · In-Person
Overcoming therapeutic resistance in oncology: A regioselective borylation platform for resurrecting and evolving nucleoside therapeutics
Yutong Zhou · Southeast University, China
The emergence of treatment resistance remains a central challenge in oncology, often stemming from the limited chemical diversity and predictable mechanisms of existing drugs. We present a transformative chemical…
- Poster · In-Person
Temporal changes in HER2 and nectin4 expression in urothelial carcinoma: Implications for antibody–drug conjugate therapy
Fu Dian · Jinling Hospital, China
Background: Urothelial carcinoma is frequently managed with chemotherapy combined with immunotherapy or antibody-drug conjugates (ADCs) targeting HER2 and Nectin4, which have shown promising efficacy in clinical…
Day 2
- Keynote · Virtual
Building bridges: Mechanisms that prevent chromatin bridge breakage in cytokinesis
George Zachos · University of Cret, Greece
Chromatin bridges are strings of mis-segregated chromatin connecting the anaphase poles or daughter nuclei in mitotic cell division and can arise from incomplete DNA replication or decatenation, or from dicentric…
- Keynote · Virtual
The art of patient conversation in oncology
Stephan Bodis · University Zurich, Switzerland
A special effort is needed to improve patient information and patient conversation in radiation oncology. This focus does not only improve patient satisfaction but also contributes to overall quality care and outcome of…
- Keynote · Virtual
Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais · Catholic University of Brasilia, Brazil
In this keynote talk, the use of the Hill model to assess the Benchmark dose (BMD), the lethal dose 50 (LD50), the cooperativity (E), and the dissociation constant (K) while analyzing cell viability data using…
- Keynote · Virtual
Multiplexed biosensor detection of cancer biomarkers
Michael Thompson · University of Toronto, Canada
Biosensor technology represents an attractive strategy for the detection and monitoring of biomarkers for disease states within the context of precision medicine. In the present paper we discuss the application of…
- Keynote · Virtual
Controlling cells: One nanoparticle at a time
Thomas Jay Webster · Brown University, United States
This presentation will cover a close to 30 year journey researching and commercializing nanotechnology for improving disease prevention, diagnosis, and treatment (including cancer) which has led to numerous products…
- Keynote · Virtual
A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya · University of California San Francisco, United States
Current screening methods—radiological imaging, DNA-based tests, and pathological assessments—often fail to detect malignancies at early stages. Despite technological advances, gene-based diagnostics specifically…
- Oral · Virtual
The role of emotion regulation, self-compassion, and perceived lifestyle discrepancy in maintaining a healthy lifestyle among breast cancer survivors
Svetlana Baziliansky · University of Haifa, Israel
Aims: An unhealthy lifestyle elevates the risk of comorbidities, cancer recurrence, and diminished quality of life among breast cancer survivors. Yet, the influence of psychosocial factors on sustaining healthy…
- Oral · Virtual
Radosavljevic's urinary screening biomarkers of the key chemical carcinogens for bladder cancer
Vladan Radosavljevic · Military Medical Academy, Serbia
The aim of the study was to examine the possibility of using the urinary concentration of 1-hydroxypyrene for screening high-risk male individuals for bladder cancer. Radosavljevi?′s urinary screening protocol for the…
- Oral · Virtual
Toll-like receptors-autophagy-PI3Akt “immune-inflammatory metabolic signalosome” in prostate cancer in the robotic prostatectomy golden era: Damage-associated molecular patterns in immunogenic cell-death?
Saumya Pandey · Indira IVF Hospital, India
Objective : I aimed to investigate the potential immunomodulatory role of complex Autophagy, Toll-like Receptors and PI3-Akt signaling networks/cross-talks in single cell immunobiology by targeting circulating tumor…
- Oral · Virtual
The role of biophysics in cancer
Ratan Kumar Sarkar · Independent Researcher, India
The proliferative biophysical structure is associated with Earth’s or Lunar time(183 or 777), Earth’s gravity(734) and Lunar gravity(0.1605 or 705) in context of 900-109(reverse) fundamental mathematical complex with a…
- Oral · Virtual
Unveiling etiological mechanisms and a targeted, non-toxic integrative approach for cancer management
Surya Prakash Tadepalli · Jai Surya Global Healthcare Center, India
Cancer has emerged as a major global public health challenge, affecting populations across all age groups. Once considered a rare and inexplicable disease, advances in biomedical sciences have established that cancer…
- Oral · Virtual
Genetic and epigenetic alterations of SOX7 in multiple myeloma and allied neoplasms
Can Küçük · Dokuz Eylul University, Turkey
Multiple myeloma (MM) is one of the most frequent hematological malignancies. Its incidence and mortality rate is globally increasing. Most MM patients experience relapse, which leads to poor prognosis. The genes…
- Oral · Virtual
Investigation of new synthetic compounds: 4-(methyl sulfanyl) phenyl-1,3,4-thiadiazol-2-amine and 1-methyl-[4-(methyl sulfanyl)phenyl]-1,3,4-thiadiazol-2-amine, for anti-cancerous activity and for p53 anti-cancer gene expression on glioblastoma cell cultures (LN-229)
Prabha Muddobalaiah · Ramaiah Institute of Technology, India
Glioblastoma Multiforme (GBM) is a stage IV brain tumour is complex and deadly diseases. There is no promising therapeutic applications for GBM, and so many drugs are developed, and screened in pre- clinical/clinical…
- Oral · Virtual
Emerging dynamics of pediatric oncology in India: A systematic meta-analysis of environmental toxins, nutritional deficits and global healthcare disparities
N D Vaswani · PGIMS, Rohtak, India
The landscape of pediatric oncology in India is undergoing a documented epidemiological transformation, with data-driven projections from the National Cancer Registry Programme (NCRP) forecasting a 12.8% escalation in…
- Oral · Virtual
Cancer awareness in teens: A hybrid cross-sectional survey and informational campaign
Alessandra Storm Mauricio · Christian Brothers High School, United States
Introduction: Cancer in adolescents and young adults (AYAs) is a worldwide devastating disease. In the US, it is among the top four causes of AYA deaths. Cancer signs/symptoms are similar to common ailments, delaying…
- Oral · Virtual
AI guided navigation of high risk incidental findings on imaging studies leads to cancer diagnoses
Kylie Dickerson · University of Arizona College of Medicine Phoenix, United States
Introduction : Artificial Intelligence (AI) is a burgeoning tool in the field of surgery. AI technology is vastly unexplored with few applications currently in use. High risk incidental findings in radiologic studies…
- Oral · Virtual
Clinical interpretation of whole genome sequencing to assess radiation treatment effects
K R Muralidhar · Karkinos Healthcare Private Limited, India
Introduction and Objective : Radiation therapy is a cornerstone of cancer treatment, yet its efficacy is often limited by inherent or acquired tumour radio resistance and the potential for long-term adverse effects.…
Day 3
- Keynote · Virtual
Nasopharyngeal carcinoma: A “different” head and neck tumour
Pietro Salvatori · Formerly, Humanitas San Pio X Hospital, Italy
As in some other sites of the head and neck, a broad range of tumours can arise in the nasopharynx: epithelial, mesenchymal, lymphoid, and neuro-ectodermal. However, naso-pharyngeal carcinoma (NPC) is the most…
- Keynote · Virtual
Theranostic nanoparticles combined particle therapy
Sandrine Lacombe · University of Paris-Saclay, France
The challenge of radiotherapy is to increase radiation damage on tumor whilst preserving healthy tissue. Particle therapy offers an alternative method whose ballistic properties improve tumor targeting. However the…
- Keynote · Virtual
Deep systems insights into the conceptual breakthrough of the noncoding RNA functional network and its role in cancer
Anyou Wang · DIFIBER LLC, United States
Noncoding RNAs (ncRNAs) transcribed from noncoding regions of the human genome are highly active and functionally significant; however, the nature of their functional system remains a subject of debate. Recent advances…
- Keynote · Virtual
MicroRNA expression in pediatric sarcoma
Atif A Ahmed · Seattle Children’s Hospital, United States
MicroRNAs are small non-coding RNA molecules that play a significant role in many physiological processes in the body, including posttranscriptional regulation of gene expression. Their expression in cancer cells can…
- Oral · Virtual
A new sensing mechanism for chromatin bridges by the abscission checkpoint in human cancer cells
Eleni Petsalaki · University of Crete, Greece
Chromatin bridges are DNA strings that link anaphase poles or daughter nuclei and are associated with carcinogenesis. DNA bridges occur from the separation of twisted, linked chromatin that is caused by problems in DNA…
- Oral · Virtual
Reconstruction after salvage surgery for laryngo-pharyngo-esophageal tumors: The experience of the National Cancer Institute of Milan, Italy (1970–2010)
Pietro Salvatori · Formerly, Humanitas San Pio X Hospital, Italy
The Head and Neck Oncology Division (HNOD) of the National Cancer Institute of Milan (NCI), once equipped with 66 beds, operating rooms, and daily outpatient clinics, has been a leading center for elective and salvage…
- Oral · Virtual
Platinum micromotors for mucosal penetration and colorectal cancer therapy
Jun Zhang · The Second Affiliated Hospital of Chongqing Medical University, China
The therapeutic outcomes of medications were restricted by the colonic mucosal barrier during the treatment of colorectal cancer (CRC). Micro/nanomotors can overcome the mucus barriers to reach deep colorectal tumors.…
- Oral · Virtual
Ultrasound-guided high-intensity focused ultrasound ablation for pancreatic cancer: Follow-up and clinical analysis
Jin Chengbing · The Second Affiliated Hospital of Chongqing Medical University, China
Objective: To evaluate the efficacy and safety of high-intensity focused ultrasound ablation in the treatment of pancreatic cancer and to analyze relevant prognostic factors. Methods: A retrospective analysis was…
- Oral · Virtual
Lifestyle, reproductive factors, and gene expression patterns in breast cancer among rural Indian women
Neetu Kalra · Azim Premji University, India
Breast cancer is one of the most common cancers among women, accounting for over 23% of all cancer-related fatalities in India. This study aimed to identify the risk factors associated with breast cancer among women…
- Oral · Virtual
Impact of diclofenac on expression of POTE family genes POTE E and POTE B in epithelial ovarian cancer cell lines
Keerthi Teja · All India Institute of Medical Sciences New Delhi, India
Ovarian Cancer (OC) is the 3rd most common gynecological cancer worldwide with high morbidity and mortality rate and Epithelial Ovarian Cancer (EOC) is the most common subtype (90%). Despite advances in treatment, late…
- Oral · Virtual
Osteopontin-induced M2 macrophage polarization via PI3K/AKT/mTOR signaling in melanoma and its inhibition by andrographolide
Venketesh K Panda · Kalinga Institute of Industrial Technology, KIIT Deemed to be University, India
Melanoma progression is critically shaped by the tumor microenvironment, where tumor- associated macrophages predominantly acquire an immunosuppressive M2-like phenotype. Osteopontin (OPN), a secreted glycoprotein…
- Oral · Virtual
Early nursing recognition and management of oncologic emergencies: A scoping review of emergency and supportive/palliative care approaches
Omar Alqaisi · Al-Zaytoonah University, Jordan
This scoping review systematically maps the evidence on nursing interventions for early recognition and management of oncologic emergencies in adults with cancer. Oncologic emergencies represent time-critical conditions…
- Oral · Virtual
Effect of Posaconazole compared to other antifungal drugs in survival & prevention of infection in patients with haematological malignancy: A systematic review
Arthi Roy · Pabna Medical College, Bangladesh
Introduction: Patients with acute leukemia who experience neutropenia after intensive chemotherapy have a high risk of developing Invasive Fungal Infections (IFIs), which can be life threatening. Although diagnostics…
- Oral · Virtual
Bio-inspired optimization and AI interpretability for melanoma classification
Sabura Banu Urundai Meeran · Saveetha Engineering College, India
The early and precise diagnosis of melanoma plays a crucial role in improving survival rates and enabling timely intervention. However, automated melanoma detection systems face challenges due to image artifacts…
- Oral · Virtual
Cancer care challenges in Gaza under crisis conditions: Field experience from an oncology nurse
Mostafa Mesbah Mahmoud Sabbah · Gaza Oncology Center, Israel
Gaza faces unique challenges in providing cancer care due to ongoing conflict, resource limitations, and disruptions in healthcare infrastructure. As an oncology nurse, I have firsthand experience managing these…
- Oral · Virtual
Uncovering tumor-suppressive roles of histone modifiers in gastric cancer through spatial transcriptomics and epigenomics
Shilpa S Dhar · The University of Texas at MD Anderson Cancer Center, United States
Gastric adenocarcinoma (GAC) remains one of the leading causes of cancer-related mortality worldwide, largely due to its late-stage diagnosis, limited treatment options, and poorly understood molecular drivers. Recent…
- Poster · Virtual
PD-1 inhibitor-induced refractory Acute Inflammatory Demyelinating Polyneuropathy (AIDP): Case report
Alec N A Jotte · RUSH MD Anderson Cancer Center, United States
Immune checkpoint inhibitors have marked a new era in contemporary cancer therapy. However, they are associated with a spectrum of immune-related adverse events (irAEs), including rare but severe neurologic toxicities…
Present your research at CIOC 2027
Abstract submissions for the 2027 program are open · March 15–17, 2027 · Village Hotel Changi, Singapore.
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Singapore · March 15–17, 2027· Hybrid · in-person & virtual
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