International Cancer Research Conference
March 24-26, 2025 | Singapore
Biology of Cancer
Cancer is a genetic disorder in which the information in cellular DNA is distorted, resulting in aberrant gene expression patterns. As a result, normal genes that control normal cellular processes like growth, survival, and invasion/motility are amplified, whereas genes that inhibit these effects are suppressed. Although non-mutational (epigenetic) alterations produced by mechanisms such as DNA methylation are becoming recognized as crucial to the process, the accumulation of mutations is the major mechanism of alteration. The so-called hallmarks and enabling characteristics of cancer are basic alterations in biological processes within cancer cells caused by abnormal gene expression. Eight distinct hallmarks and two additional so-called enabling traits can be used to understand cancer's biological behavior. In cancer medicine, a better understanding of the biological basis of these processes has transformed diagnosis, treatment and prognosis.
- Oncogenes
- Tumor Suppressor Genes
- Apoptotic pathways
- Cellular immortalization
- Mutagens
- Invasion and metastasis
- Immune checkpoints
Rajvir Dahiya
University of California San Francisco, United States
Atif A Ahmed
Seattle Children’s Hospital, United States
Michael Thompson
University of Toronto, Canada
Mariola Wioletta Borowska
Maria Sklodowska-Curie National Research Institute of Oncology, Poland
Andrea González Báez
Autonomous University of Nuevo Leon, Mexico
Qian Zhang
The Affiliated Changzhou Second People’s Hospital of Nanjing Medical University, China
Zheng Wang
Shanghai Jiao Tong University School of Medicine, ChinaSubmit your abstract Today
Title : A novel mRNA genomic technology for precision medicine, early cancer diagnosis, prognosis, treatment follow-up and cancer gene therapy
Rajvir Dahiya, University of California San Francisco, United States
Title : The future of pharmacogenetic polymorphism, pharmacogenomics and pharmamicrobiome in cancer treatment
Bene Ekine-Afolabi, University of East London, United Kingdom
Title : Biosensor-based detection of cancer biomarkers
Michael Thompson, University of Toronto, Canada
Title : Hospital care for cancer patients - safety, quality of care, education and respect for patient’s rights
Mariola Wioletta Borowska, Maria Sklodowska-Curie National Research Institute of Oncology, Poland
Title : Importin7 induces M2 macrophage and promotes the progress of colorectal cancer by regulating the nucleus translocation of GRP78
Changjiang Yang, Peking University People's Hospital, China
Title : Cancer-associated fibroblasts derived soluble CADM1 predicts response to neoadjuvant chemoimmunotherapy in lung cancer
Jian Li, Shanghai Jiaotong University, China