Cancer is a term used to represent a collection of more than 150 diseases defined by uncontrolled cell growth and spread. The pathophysiology of cancer is complicated. Pathologists are doctors who specialize in the study of disease in all of its manifestations. This comprises the disease's source, diagnosis, pathogenesis (how the disease develops), mechanism, and natural course. They also deal with biological properties, disease development, and prognosis or outcome. After the introduction of technologies such as immunohistochemistry, flow cytometry, and molecular biologic approaches to cancer diagnosis, the pathology of cancers and other complicated diseases has changed dramatically.
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Title : Deubiquitylase USP31 induces autophagy and promotes the progression in lung squamous cell carcinoma cells by stabilizing E2F1 expression
Qian Zhang, The Affiliated Changzhou Second People’s Hospital of Nanjing Medical University, China
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Luca Roncati, University of Modena and Reggio Emilia, Italy
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Bene Ekine-Afolabi, ZEAB Therapeutic Ltd, United Kingdom
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K.P.Mishra, Asian Association for Radiation Research, India