Liquid tumor models, which use blood or other bodily fluids to study cancer, offer a less invasive alternative to traditional tissue biopsies. These models enable real-time monitoring of cancer progression and the detection of genetic and molecular changes in circulating tumor cells (CTCs) or tumor-derived extracellular vesicles. In silico simulations, computer-based models that replicate the biological processes of cancer, also play a vital role in predicting the behavior of tumors and assessing the effects of potential therapies. Combining liquid tumor models with in silico simulations enhances the precision of cancer research, providing a more dynamic and comprehensive understanding of tumor biology. These innovations promise to improve early diagnosis, monitor treatment responses, and facilitate the development of personalized cancer therapies.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China