Advancements in cancer diagnostics are revolutionizing early detection and disease monitoring, offering more precise and minimally invasive alternatives to traditional tissue biopsies. Among these innovations, Liquid Biopsy & MRD (Minimal Residual Disease) testing have emerged as crucial tools for understanding tumor dynamics in real-time. Liquid biopsy analyzes circulating tumor DNA, RNA, or cells in blood samples, providing a snapshot of the molecular landscape of cancer without the need for invasive procedures. This approach enables early detection of recurrence, identification of actionable mutations, and monitoring of treatment response, while MRD assessment helps quantify residual disease following therapy. Together, these technologies allow clinicians to make informed decisions about therapy adjustments and predict patient outcomes with higher accuracy, ultimately supporting more personalized cancer care.
The clinical impact of Liquid Biopsy & MRD is becoming increasingly evident across multiple cancer types, including hematologic malignancies and solid tumors. By detecting minimal residual disease at a molecular level, clinicians can intervene earlier, optimize treatment regimens, and improve the likelihood of durable remission. Ongoing research is refining the sensitivity, specificity, and predictive value of these assays, as well as exploring their integration with immunotherapies, targeted agents, and precision oncology platforms. As these tools become standard practice, liquid biopsy and MRD monitoring are poised to redefine cancer management, providing a dynamic, non-invasive means to guide therapy, track disease progression, and enhance long-term survival outcomes for patients worldwide.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : Nanomedicine in humans: 30 years of fighting diseases
Thomas J Webster, Northeastern University, United States
Title : Diagnosis and treatment of primary cardiac lymphoma in an immunocompetent 27-year-old man
Moataz Taha Mahmoud Abdelsalam, Madinah Cardiac Center, Saudi Arabia
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Multiplexed biosensor detection of cancer biomarkers
Michael Thompson, University of Toronto, Canada
Title : Personalized and Precision Medicine (PPM) through the view of biodesign-inspired translational research: An option for clinical oncologists, caregivers, and consumers to realize the potential of genomics-informed care to secure human biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation