Cancer in children, adolescents, and young adults presents unique biological, clinical, and psychosocial challenges that require specialized care. Pediatric & AYA Oncology focuses on the diagnosis, treatment, and long-term management of malignancies in these age groups, which often differ in tumor types, biology, and response to therapy compared to adult cancers. Advances in molecular profiling, genomics, and targeted therapies have improved risk stratification and personalized treatment approaches, enhancing survival while minimizing long-term side effects. Multidisciplinary teams—including pediatric oncologists, hematologists, surgeons, radiation specialists, and supportive care providers—work collaboratively to optimize outcomes while addressing the developmental, educational, and emotional needs of young patients. Early intervention, precise treatment planning, and family-centered care are critical components in improving survival and quality of life.
The evolving field of Pediatric & AYA Oncology emphasizes precision medicine, survivorship, and psychosocial support tailored to age-specific needs. Clinical trials continue to explore innovative therapies, including immunotherapy, targeted agents, and combination regimens, to enhance response rates and reduce relapse risk. Supportive care programs focus on managing treatment-related toxicities, promoting mental health, and facilitating educational and social development. As research advances, integrating molecular diagnostics, personalized therapies, and multidisciplinary care ensures that pediatric and AYA patients receive comprehensive, adaptive treatment. These strategies not only aim to improve survival but also empower young patients to achieve long-term health, resilience, and quality of life throughout and beyond their cancer journey.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : Nanomedicine in humans: 30 years of fighting diseases
Thomas J Webster, Northeastern University, United States
Title : Diagnosis and treatment of primary cardiac lymphoma in an immunocompetent 27-year-old man
Moataz Taha Mahmoud Abdelsalam, Madinah Cardiac Center, Saudi Arabia
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Multiplexed biosensor detection of cancer biomarkers
Michael Thompson, University of Toronto, Canada
Title : Personalized and Precision Medicine (PPM) through the view of biodesign-inspired translational research: An option for clinical oncologists, caregivers, and consumers to realize the potential of genomics-informed care to secure human biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation