Cancer and Aging

• Mechanisms of Cancer in the Aging Population
• Geriatric Oncology: Tailoring Treatments for Older Adults
• Interactions Between Aging and Cancer Therapies
• Epigenetic Changes in Aging and Cancer

Aging is a significant risk factor for cancer, with most diagnoses occurring in older adults. As we age, genetic mutations accumulate, and immune system efficiency declines, increasing cancer susceptibility. Cellular senescence, an aging hallmark, promotes a pro-inflammatory environment, contributing to tumor development.

For older patients, cancer treatment poses unique challenges. Comorbidities and reduced physiological reserves often limit the feasibility of aggressive therapies. Advances in geriatric oncology are now tailoring treatments to the specific needs of aging individuals, focusing on balancing efficacy and quality of life.

Studying the interplay between cancer and aging not only enhances understanding of disease progression but also drives innovations in early detection, prevention, and personalized care for an aging global population.