In modern oncology, the need to bridge the gap between clinical research and everyday patient care has become increasingly important. This has led to a growing emphasis on Real-World Data & Outcomes, which capture insights from routine clinical practice beyond the controlled settings of clinical trials. Real-world data, derived from electronic health records, registries, insurance claims, and patient-reported outcomes, offer a more comprehensive understanding of how therapies perform across diverse populations. These data help identify treatment patterns, safety signals, and long-term effectiveness that may not be evident in traditional studies. By integrating real-world evidence into oncology research, clinicians and policymakers can make more informed decisions, enhance patient care, and optimize resource allocation across healthcare systems.
The integration of Real-World Data & Outcomes is transforming how cancer therapies are evaluated, regulated, and reimbursed. Pharmaceutical companies and healthcare providers are increasingly using these insights to refine treatment guidelines, design adaptive clinical trials, and assess the true value of novel therapies. Advances in data analytics, machine learning, and interoperability are enhancing the accuracy and utility of real-world evidence, allowing for continuous learning within oncology care systems. As these methodologies mature, they promise to complement randomized clinical trials, ensuring that therapeutic innovations translate into meaningful improvements in patient survival, quality of life, and healthcare efficiency across global cancer populations.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : Nanomedicine in humans: 30 years of fighting diseases
Thomas J Webster, Northeastern University, United States
Title : Diagnosis and treatment of primary cardiac lymphoma in an immunocompetent 27-year-old man
Moataz Taha Mahmoud Abdelsalam, Madinah Cardiac Center, Saudi Arabia
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Multiplexed biosensor detection of cancer biomarkers
Michael Thompson, University of Toronto, Canada
Title : Personalized and Precision Medicine (PPM) through the view of biodesign-inspired translational research: An option for clinical oncologists, caregivers, and consumers to realize the potential of genomics-informed care to secure human biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation