Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Abstract:
Objective: The purpose of this study is to investigate and analyze the nutritional risk anditsdynamic changing trend of breast cancer patients in the process of disease treatment.
Methods: The nutritional risk screening data of breast cancer patients treated in our hospital from January 1, 2022 to June 13, 2025 were collected retrospectively, including the age, sex, recurrence or metastasis of the patients and the score of NRS2002. SPSS 30.0 was usedforstatistical analysis of data.
Results: A total of 10032 breast cancer patients were includedinthe cross-sectional data analysis. There were 667 breast cancer patients with NRS2002score≥3, accounting for 6.65%. The average BMI of 10032 breast cancer patients was(23.35±3.38), and the NRS2002 score was higher and the BMI was lower for breast cancerpatients with age≤40 years and recurrence or metastasis. A total of 117 patients withbreastcancer were included in the longitudinal data analysis. During the five periods of Abstract Submission Template investigation, the NRS2002 score gradually increased, and the time effect of NRS2002scoreof breast cancer patients of different ages and whether they relapsed or not was significantat different time points (P=0.001). The BMI gradually decreased, and the time effect, inter- group effect and interaction effect of the BMI of breast cancer patients of different agesatdifferent time points were not significant. 117 patients with breast cancer were dividedintotwo groups according to their recurrence or metastasis. The time effect and interactioneffect of BMI of breast cancer patients at different time points were significant (P<0.05).
Conclusion: There is a certain degree of nutritional risk in patients with breast cancer, andthe nutritional risk is gradually increasing in the process of disease treatment. Ageandrecurrence or metastasis are important factors affecting the nutritional risk of patients. Clinically, individualized nutritional monitoring and intervention should be implementedforbreast cancer patients with different ages, recurrence or metastasis status and treatmentstage.
