Interactions Between Aging and Cancer Therapies

The interactions between aging and cancer therapies are complex and often result in altered responses to treatment. Older adults are more likely to experience intensified side effects from chemotherapy, radiation, or targeted therapies, partly due to changes in organ function, drug metabolism, and immune system efficacy. Additionally, age-related factors like cognitive decline and frailty can impact the patient’s ability to tolerate and adhere to treatment regimens. To optimize therapeutic outcomes, it is crucial to tailor cancer treatments for older patients, considering both the biological aspects of aging and the potential for drug interactions and toxicity.