2nd Edition of International Cancer & Immuno-Oncology Conference
March 19-21, 2026 | Singapore
Epigenetics in Cancer: Understanding the role of epigenetic changes in cancer progression.
Epigenetics is reshaping our understanding of cancer by exploring the heritable changes in gene expression that do not involve alterations in DNA sequences. Epigenetic modifications, such as DNA methylation, histone modifications, and non-coding RNAs, play a crucial role in regulating gene activity and cellular behavior. In cancer, these changes often silence tumor suppressor genes or activate oncogenes, driving tumorigenesis. Unlike genetic mutations, epigenetic alterations are potentially reversible, making them attractive targets for therapeutic intervention. Drugs like DNA methyltransferase inhibitors and histone deacetylase inhibitors have shown promise in reactivating silenced genes and restoring normal cellular functions. Epigenetics also holds potential in early cancer detection, as specific epigenetic patterns serve as biomarkers in liquid biopsies. By unraveling the complexities of the epigenetic landscape, researchers aim to develop innovative treatments and diagnostic tools that could transform cancer care.
Rajvir Dahiya
University of California San Francisco, United States
Atif A Ahmed
University of Washington-Seattle Children’s Hospital, United States
Anyou Wang
DIFIBER LLC, United States
Paulo Cesar De Morais
Catholic University of Brasilia, Brazil
Allen Chen
Olympic Medical Center, United States
Shilpa S Dhar
UT MD Anderson Cancer Center, United States
Ritu Khanna
University of Manchester, United KingdomSubmit your abstract Today
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China