2nd Edition of International Cancer & Immuno-Oncology Conference
March 19-21, 2026 | Singapore
Epigenetics and Gene Regulation
Epigenetics and gene regulation are key factors in the development and progression of cancer, influencing how genes are expressed without changing the genetic code. These regulatory mechanisms, such as DNA methylation, histone modifications, and non-coding RNA activity, can have a profound impact on cellular behavior. In cancer, epigenetic alterations often lead to the activation of genes that promote tumor growth or the silencing of genes that prevent cancer, such as tumor suppressors. Unlike genetic mutations, which are permanent, epigenetic modifications can be reversible, making them an appealing target for cancer therapies. Researchers are exploring ways to manipulate these epigenetic changes to restore normal gene function and inhibit cancer cell growth. By understanding the role of epigenetics in cancer, scientists are also identifying new potential biomarkers for early detection and better predicting how tumors will respond to specific treatments. This approach offers promise for developing more precise and less harmful treatments for cancer patients.
Rajvir Dahiya
University of California San Francisco, United States
Atif A Ahmed
University of Washington-Seattle Children’s Hospital, United States
Anyou Wang
DIFIBER LLC, United States
Paulo Cesar De Morais
Catholic University of Brasilia, Brazil
Allen Chen
Olympic Medical Center, United States
Shilpa S Dhar
UT MD Anderson Cancer Center, United States
Ritu Khanna
University of Manchester, United KingdomSubmit your abstract Today
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China