Translational research is the bridge between laboratory science and clinical practice, enabling the rapid application of discoveries from the bench to the bedside. It involves converting insights from cancer biology, genetics, and molecular pathways into new diagnostic tools, treatment strategies, and prevention methods that can be tested in clinical trials. Translational research is focused on improving clinical trial design, identifying biomarkers that predict treatment responses, and enhancing patient recruitment strategies to ensure diverse representation in studies. By refining these aspects, translational research accelerates the process of developing innovative, evidence-based treatments that can significantly improve patient outcomes. This approach emphasizes collaboration between researchers, clinicians, and the healthcare system to bring cutting-edge science directly to those in need, driving meaningful improvements in cancer care.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China