RNA therapeutics represent a promising frontier in cancer research, offering targeted treatment options with potential for fewer side effects. These therapies utilize various RNA molecules, including messenger RNA (mRNA), small interfering RNA (siRNA), and microRNA (miRNA), to regulate gene expression or directly target cancer cells. mRNA vaccines, like those developed for COVID-19, stimulate the immune system to recognize and attack cancer-specific antigens. siRNA molecules can silence oncogenes or block proteins essential for tumor growth. Additionally, miRNAs regulate gene expression and control cellular processes implicated in cancer progression. By harnessing the power of RNA, researchers aim to develop precise, personalized treatments that disrupt cancer pathways while sparing healthy tissues. As this field advances, RNA therapeutics hold immense potential to revolutionize cancer care, offering hope for more effective and tailored treatment strategies.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China