Overcoming Drug Resistance and Toxicity

Overcoming drug resistance and toxicity remains a major challenge in cancer therapy. Resistance arises from genetic mutations in cancer cells, leading to treatment inefficacy, while toxicity affects patients’ quality of life. Strategies to address these issues include combination therapies, sequential treatment regimens, and next-generation drugs designed to bypass resistance mechanisms. Biomarker-driven approaches allow for better prediction of drug responses, enabling personalized treatment plans. Advances in nanotechnology and drug design continue to mitigate toxicity, ensuring safer and more effective cancer treatments for patients worldwide.