Neoplasia, the process of abnormal and uncontrolled cell growth, underpins cancer development and progression. This pathological proliferation results in benign or malignant tumors, with malignant neoplasms exhibiting invasive and metastatic properties. Recent cancer research focuses on elucidating the molecular mechanisms driving neoplastic transformation, including genetic mutations, epigenetic alterations, and dysregulated signaling pathways. Advances in understanding the tumor microenvironment and its role in supporting neoplastic growth have highlighted the importance of targeting not only the cancer cells but also the surrounding stromal and immune cells. Innovative therapies, such as immunotherapy, targeted treatments, and personalized medicine, are being developed to exploit these insights, aiming to improve patient outcomes and minimize adverse effects. The dynamic interplay between genetic predisposition and environmental factors continues to be a crucial area of investigation in the quest to prevent and treat neoplasia effectively.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China