Myelodysplastic syndromes (MDS) constitute a group of blood disorders characterized by dysfunctional bone marrow, leading to ineffective blood cell production. While not always cancerous, MDS can progress to acute myeloid leukemia (AML), a more aggressive form of blood cancer. Cancer research in MDS focuses on understanding the molecular mechanisms driving disease progression and identifying novel therapeutic targets. Recent advancements include the development of targeted therapies aimed at restoring normal blood cell production and improving patient outcomes. Additionally, studies exploring the role of immunotherapy and epigenetic modifiers in MDS management offer promising avenues for future treatment strategies. Continued research efforts are essential to unravel the complexities of MDS and devise more effective therapies for patients afflicted with this challenging condition.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China