Molecular Oncologists investigate the genetic and molecular factors that contribute to the development and progression of cancer. By examining genetic mutations, alterations in DNA, and changes in cellular pathways, they identify the underlying causes of cancer and how tumors grow and spread. Their research is pivotal in uncovering specific biomarkers that can be used for early detection and precise diagnosis, as well as for determining which treatments will be most effective for individual patients. Through a deeper understanding of the molecular drivers of cancer, molecular oncologists develop targeted therapies that attack cancer cells while sparing healthy tissue, leading to more effective treatments with fewer side effects.
Furthermore, molecular oncologists play a key role in the field of precision medicine, tailoring cancer therapies to the genetic profile of both the patient and the tumor. This personalized approach allows for more efficient treatments and better outcomes. Their work also extends to the development of immunotherapies, which use the body's immune system to fight cancer, providing hope for patients with previously difficult-to-treat cancers. By utilizing advancements in genomics, bioinformatics, and technology, molecular oncologists continue to lead the charge in improving cancer treatment, aiming for therapies that are not only more precise but also more durable, offering patients new hope for long-term survival.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China