Hereditary cancers result from genetic mutations passed through families, increasing susceptibility to certain cancer types. BRCA1 and BRCA2 mutations are strongly associated with breast, ovarian, and pancreatic cancers, with targeted therapies like PARP inhibitors showing promise. Lynch syndrome-related cancers, including colorectal and endometrial cancers, are addressed through genetic counseling, regular screenings, and immunotherapy options. Research in hereditary cancers prioritizes identifying mutation carriers, understanding gene-environment interactions, and developing prevention strategies. The integration of genetic testing into clinical practice aids in early detection and personalized treatment planning.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China