Familial cancer refers to cancers that occur more frequently within families due to shared genetic mutations. Understanding the genetic basis of familial cancer is crucial for cancer research, as it helps identify individuals at higher risk and allows for tailored prevention and treatment strategies. Researchers study familial cancer syndromes to uncover specific genetic alterations that predispose individuals to certain types of cancer, such as BRCA1 and BRCA2 mutations in breast and ovarian cancer. By elucidating these genetic factors, scientists can develop targeted therapies and screening protocols to detect cancer at earlier stages, potentially saving lives. Moreover, studying familial cancer sheds light on broader mechanisms of carcinogenesis, offering insights into the molecular pathways underlying various cancer types and driving advancements in precision medicine.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China