Cancer immunometabolism explores the intricate interplay between cancer cells, the immune system, and cellular metabolism. Research in this field unveils how cancer cells reprogram their metabolic pathways to evade immune surveillance and thrive within the hostile tumor microenvironment. Key mechanisms include alterations in nutrient uptake, such as increased glucose consumption and glutamine addiction, which fuel cancer cell proliferation and immune evasion strategies. Additionally, immune cells undergo metabolic reprogramming to adapt their function and efficacy against cancer cells. Understanding these metabolic nuances opens avenues for developing innovative cancer therapies that target metabolic vulnerabilities in both cancer cells and immune cells, enhancing the efficacy of immunotherapy and paving the way for more personalized and effective cancer treatment strategies.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China