Cancer Immunometabolism

Cancer immunometabolism explores the intricate interplay between cancer cells, the immune system, and cellular metabolism. Research in this field unveils how cancer cells reprogram their metabolic pathways to evade immune surveillance and thrive within the hostile tumor microenvironment. Key mechanisms include alterations in nutrient uptake, such as increased glucose consumption and glutamine addiction, which fuel cancer cell proliferation and immune evasion strategies. Additionally, immune cells undergo metabolic reprogramming to adapt their function and efficacy against cancer cells. Understanding these metabolic nuances opens avenues for developing innovative cancer therapies that target metabolic vulnerabilities in both cancer cells and immune cells, enhancing the efficacy of immunotherapy and paving the way for more personalized and effective cancer treatment strategies.