Cancer gene therapy, a promising frontier in oncology, targets the genetic abnormalities underlying cancer. This approach involves introducing genetic material into cancerous cells to inhibit their growth or trigger cell death. One strategy employs viral vectors to deliver therapeutic genes selectively to tumor cells, while sparing healthy tissue. Another method utilizes gene editing tools like CRISPR to precisely alter cancer-related genes, correcting mutations or deactivating oncogenes. While still in its infancy, gene therapy holds immense potential for personalized cancer treatment, offering hope for more effective and targeted therapies with fewer side effects. However, challenges such as off-target effects and immune responses remain hurdles to overcome in realizing the full potential of this innovative approach.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China