Exploring the intricate dance of cancer autophagy unveils a nuanced battlefield in cancer research. This cellular self-degradation mechanism assumes a Janus-faced role: on one front, it fortifies cancer cells, bestowing resilience amidst chemotherapy onslaughts; on the other, it can act as a saboteur, triggering cancer cell demise. Balancing these opposing forces presents a tantalizing opportunity for therapeutic breakthroughs. Scientists delve into a myriad of approaches, from pharmacological concoctions to genetic manipulations, aiming to tip the scales in favor of cancer cell vulnerability. Deciphering the cryptic language of cancer autophagy promises not only novel treatment strategies but also a deeper understanding of the disease's mechanics, fostering tailored interventions and bolstering the fight against cancer.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China