Systemic therapy stands as a cornerstone in contemporary cancer treatment, representing a holistic approach that targets cancer cells throughout the body. This modality encompasses chemotherapy, targeted therapy, immunotherapy, and hormone therapy, each tailored to disrupt cancer's growth and spread. Chemotherapy employs cytotoxic drugs to eradicate rapidly dividing cancer cells, while targeted therapy zeroes in on specific molecular alterations driving cancer progression. Immunotherapy harnesses the body's immune system to recognize and destroy cancer cells, while hormone therapy interferes with hormone signaling pathways crucial for certain cancers, like breast and prostate cancer. These systemic approaches not only combat primary tumors but also address metastatic disease, enhancing survival rates and improving patients' quality of life. As cancer research continues to unveil novel therapeutic targets, systemic therapies remain pivotal in the evolving landscape of oncology.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China