Primary CNS lymphoma (PCNSL) is a rare form of non-Hodgkin lymphoma that affects the central nervous system, including the brain, spinal cord, and eyes. Unlike other lymphomas, it primarily manifests within the brain, leading to symptoms such as headaches, cognitive dysfunction, and vision problems. Research on PCNSL focuses on understanding its unique biology and developing targeted therapies due to its limited response to traditional treatments like chemotherapy. Recent studies delve into the genetic mutations driving its growth and potential immunotherapies that harness the body's immune system to fight cancer cells specifically within the CNS. By unraveling the intricacies of PCNSL, researchers aim to improve diagnostic methods and devise more effective treatment strategies tailored to this challenging disease.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China