Plasma cell neoplasms are a group of disorders characterized by the abnormal proliferation of plasma cells, a type of white blood cell that produces antibodies. The most well-known plasma cell neoplasm is multiple myeloma, a cancer of plasma cells that infiltrates the bone marrow. Despite significant advancements in treatment, including novel immunotherapies and targeted therapies, multiple myeloma remains incurable and can be challenging to manage due to its heterogeneity and potential for relapse. Research in this field focuses on understanding the underlying genetic and molecular mechanisms driving plasma cell neoplasms, identifying novel therapeutic targets, and developing personalized treatment strategies to improve patient outcomes. Emerging therapies such as chimeric antigen receptor (CAR) T-cell therapy offer promising avenues for more effective and durable responses in patients with relapsed or refractory disease.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China