Pheochromocytoma, a rare tumor of the adrenal glands, presents unique challenges in cancer research. These tumors, though usually benign, can be malignant and secrete excessive amounts of adrenaline, leading to severe hypertension and other life-threatening complications. Understanding the genetic underpinnings of pheochromocytoma is crucial for tailored treatment approaches. Recent research focuses on identifying genetic mutations, such as those in the RET, VHL, and SDH genes, which predispose individuals to this condition. Advances in imaging techniques aid in early detection and precise surgical removal, improving patient outcomes. Moreover, exploring novel targeted therapies and immunotherapies offers hope for more effective treatments, particularly for metastatic or recurrent cases. Collaborative efforts between clinicians, geneticists, and researchers are essential to unravel the complexities of pheochromocytoma and develop personalized strategies for management.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China