Neoadjuvant chemotherapy stands as a pivotal strategy in modern cancer research and treatment paradigms. Unlike traditional chemotherapy given after surgery, neoadjuvant therapy administers drugs prior to surgical intervention. This approach serves multiple purposes. Firstly, it aims to shrink tumors, making them more operable and potentially increasing the likelihood of complete surgical resection. Secondly, it provides an opportunity to assess tumor response to specific drugs, aiding in treatment tailoring for individual patients. Additionally, neoadjuvant chemotherapy can serve as a "real-time" test for drug efficacy, offering valuable insights into tumor biology and drug resistance mechanisms. By integrating chemotherapy into the preoperative phase, this approach represents a dynamic tool in the quest for more personalized and effective cancer care.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China