Malignant fibrous histiocytoma (MFH), now termed undifferentiated pleomorphic sarcoma, is a rare soft tissue sarcoma characterized by aggressive growth and high metastatic potential. Research in this area focuses on understanding its molecular underpinnings and identifying targeted therapies. Recent studies delve into genomic profiling to unravel the genetic alterations driving MFH development, offering insights into potential therapeutic targets. Immunotherapy, particularly immune checkpoint inhibitors, emerges as a promising avenue, enhancing the body's immune response against MFH. Additionally, advancements in imaging techniques aid in early detection and accurate staging, optimizing treatment strategies. Collaborative efforts among researchers, clinicians, and patients drive progress toward improved outcomes for individuals battling this challenging cancer.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China