Intravitreal chemotherapy, a cutting-edge approach in cancer research, involves the direct delivery of anticancer drugs into the vitreous cavity of the eye. This method is primarily utilized in the treatment of intraocular malignancies like retinoblastoma and uveal melanoma. By bypassing systemic circulation, intravitreal chemotherapy minimizes systemic side effects while maximizing drug concentration at the tumor site, enhancing therapeutic efficacy. Additionally, it offers a promising alternative when conventional therapies such as radiation or surgery are contraindicated or ineffective. Despite its potential, challenges such as drug toxicity and the risk of ocular complications persist, necessitating further refinement and clinical investigation. Nonetheless, intravitreal chemotherapy stands as a beacon of hope, showcasing the relentless pursuit of innovative strategies to combat cancer while preserving ocular function and quality of life.
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