Esophageal adenocarcinoma (EAC) is a malignant tumor that originates in the cells lining the esophagus, the muscular tube that connects the throat to the stomach. Despite being relatively uncommon, EAC represents a significant health concern due to its aggressive nature and poor prognosis. Cancer research in this field aims to elucidate the underlying molecular mechanisms driving EAC development, identify biomarkers for early detection, and discover targeted therapies for more effective treatment. Recent advancements include the exploration of immunotherapies, such as checkpoint inhibitors, and the investigation of novel targeted agents aimed at specific genetic alterations frequently found in EAC. Additionally, efforts are directed towards understanding the role of lifestyle factors, such as obesity and gastroesophageal reflux disease, in EAC development, paving the way for preventive strategies and personalized treatment approaches.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China