2nd Edition of International Cancer & Immuno-Oncology Conference
March 19-21, 2026 | Singapore
Chronic Myeloproliferative Neoplasms
Chronic myeloproliferative neoplasms (MPNs) are a group of blood cancers characterized by the overproduction of mature blood cells in the bone marrow. This excessive production leads to an increased risk of blood clots, bleeding, and a potential transformation to acute leukemia. Recent research in cancer biology has shed light on the molecular mechanisms driving MPNs, uncovering mutations in genes such as JAK2, CALR, and MPL, which play crucial roles in regulating blood cell production. Targeted therapies, including JAK inhibitors like ruxolitinib, have revolutionized the treatment landscape, offering improved symptom control and potentially altering the disease course. Moreover, emerging immunotherapies and combination treatment approaches hold promise for enhancing patient outcomes and providing a deeper understanding of MPN biology, paving the way for more effective and personalized treatment strategies in the future.
Rajvir Dahiya
University of California San Francisco, United States
Atif A Ahmed
University of Washington-Seattle Children’s Hospital, United States
Anyou Wang
DIFIBER LLC, United States
Paulo Cesar De Morais
Catholic University of Brasilia, Brazil
Allen Chen
Olympic Medical Center, United States
Shilpa S Dhar
UT MD Anderson Cancer Center, United States
Ritu Khanna
University of Manchester, United KingdomSubmit your abstract Today
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China