Chemotherapeutic agents represent a cornerstone in cancer treatment, comprising a diverse array of drugs designed to combat the proliferation of cancer cells. These agents operate through various mechanisms, including inhibiting cell division, disrupting DNA replication, and inducing apoptosis (cell death) in malignant cells. Over the years, research has led to the development of increasingly targeted and personalized chemotherapies, aiming to minimize adverse effects on healthy tissues while maximizing efficacy against tumors. From traditional cytotoxic drugs to modern molecularly targeted therapies and immunotherapies, the landscape of chemotherapeutic options continues to evolve. Ongoing cancer research focuses on optimizing drug delivery methods, overcoming drug resistance, and exploring synergistic combinations to enhance treatment outcomes and improve the quality of life for cancer patients.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China