Cancer genome exploration delves deep into the intricate genetic fabric that underpins cancer's origin and progression. By meticulously dissecting the DNA blueprint within cancerous cells, researchers uncover pivotal mutations dictating tumor growth, spread, and resistance to treatment. This genomic scrutiny not only unveils the diverse molecular mechanisms propelling cancer but also heralds a new era of tailored therapies, finely tuned to the individual genetic makeup of patients. Advanced methodologies such as next-generation sequencing unravel the complexity of various cancer types, offering profound insights into potential therapeutic targets and predictive markers. Initiatives like The Cancer Genome Atlas (TCGA) serve as vast treasure troves of genomic data, fueling collaborative endeavors aimed at unraveling cancer's genomic mysteries and revolutionizing oncology. Through relentless exploration of the cancer genome, scientists endeavor to unearth innovative strategies for early detection, precise intervention, and ultimately, the triumph over cancer's formidable grip.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China