Cancer research delves deep into the intricate interplay of genetics and epigenetics, unraveling the molecular mysteries driving cancer initiation and progression. Genetic mutations, whether inherited or acquired, disrupt the delicate balance of cell growth regulation, fueling tumorigenesis. Meanwhile, epigenetic modifications, like DNA methylation and histone alterations, can covertly switch genes on or off, orchestrating a cellular landscape conducive to cancer development. Understanding these dynamic processes not only sheds light on cancer etiology but also offers tantalizing prospects for targeted therapies and precision medicine interventions. By deciphering the genetic and epigenetic signatures underlying different cancers, researchers are forging new frontiers in diagnosis, prognosis, and personalized treatment strategies, ultimately striving towards more effective cancer management.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China