Cancer chemotherapy and pharmacology represent critical fronts in cancer research, aiming to enhance treatment efficacy while mitigating side effects. Chemotherapy drugs target rapidly dividing cancer cells, disrupting their growth and proliferation. However, these drugs can also affect healthy cells, leading to adverse reactions like nausea, hair loss, and immune suppression. Advancements in pharmacology focus on developing targeted therapies, such as immunotherapy and molecularly targeted agents, which selectively attack cancer cells while sparing healthy tissue. Additionally, research explores novel drug delivery systems to improve drug distribution and minimize toxicity. Understanding the intricate mechanisms of cancer cell biology and drug interactions is paramount for refining chemotherapy regimens and designing more personalized treatment approaches, ultimately striving for better outcomes and improved quality of life for cancer patients.
Title : A novel blood-based mRNA genomics technology for cancer diagnosis and treatment
Rajvir Dahiya, University of California San Francisco, United States
Title : tRNA-derived fragment 3′tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer
Feng Yan, The Affiliated Cancer Hospital of Nanjing Medical University, China
Title : Integrating single-cell and spatial transcriptomics to uncover and elucidate GP73-mediated pro-angiogenic regulatory networks in hepatocellular carcinoma
Jiazhou Ye, Guangxi Medical University Cancer Hospital, China
Title : Unveiling the synergism of radiofrequency therapy and graphene nanocomposite in tumor cell viability assay
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Analysis of the dynamic evolution and influencing factors of nutritional risk in breast cancer patients during treatment
Jingwen Yan, Sun Yat-sen University, China
Title : Integrative multi-omics reveals metabolic–stemness coupling and novel therapeutic targets in osteosarcoma chemoresistance
Jinyan Feng, Tianjin Medical University Cancer Institute and Hospital, China