The full CIOC 2027 scientific program across 3 days — keynotes, oral presentations, and posters. Talks are ordered by program prominence within each day.
Day 1
- Keynote · In-Person
Long-read sequencing reveals dynamic features of human malignancies
Jianhua Luo · University of Pittsburgh School of Medicine, United States
The protein diversity of mammalian cells is determined by arrays of isoforms from genes. Genetic mutation is essential in species evolution and cancer development. Accurate Long-read transcriptome sequencing at…
- Keynote · In-Person
Nanomedicine in over 45,000 patients and no cancer
Thomas Jay Webster · Brown University, United States
Nanomedicine is the use of nanomaterials to improve disease prevention, detection, and treatment which has resulted in hundreds of US FDA approved medical products. While nanomedicine has been around for several…
- Keynote · In-Person
Personalized and precision medicine (PPM) through the view of bio design-inspired translational research: An option for clinical oncologists, caregivers and consumers to realize the potential of genomics-informed care to secure human biosafetyPersonalized and precision medicine (PPM) through the view of bio design-inspired translational research: A
Sergey Suchkov · N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized and precision medicine (PPM). Meanwhile, the era of genomics-based med-icine and thus…
- Keynote · In-Person
Theranostic nanoparticles – radiation therapies combined protocols
Sandrine Lacombe · University of Paris-Saclay, France
Radiotherapy is used for 50% of patients. The challenge is to improve efficiency and tumor targeting whilst preserving healthy tissue and spare side effects. The development of radioenhancing nanoparticles (REN) capable…
- Keynote · In-Person
Next generation tissue proteomics in cancer research
Atif A Ahmed · Seattle Children’s Hospital, United States
Protein expression methods are fundamental to clinical cancer research where they are used to identify diagnostic and prognostic biomarkers that facilitate patient management. These methods can be applied to fluid and…
- Oral · In-Person
Personalized and precision medicine as a unique avenue to have the healthcare model renewed to secure national biosafety: To get cancer treated or cured by integrating multifaceted approaches focusing on immunooncology?
Sergey Suchkov · N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
To achieve the implementation of Personalized & Precision Oncology (PPO), it is necessary to create a fundamentally new strategy based upon the recognition of bi-omarkers long before the disease clinically manifests…
- Oral · In-Person
Tumor resectability and pathologic response after neoadjuvant long-course chemoradiotherapy for locally advanced rectal cancer in a resource-limited setting
Samrawit S Halake · Kampala International University, Uganda
Purpose: In resource-limited settings, locally advanced rectal cancer (LARC) often presents at advanced stages. Long-course chemoradiotherapy (LCCRT) remains a cornerstone of neoadjuvant therapy, yet outcome data from…
- Oral · In-Person
Horizon Spectra: A comprehensive cancer genomics tertiary platform for ultra-rapid analysis
Mohammed Uddin · GenomeArc Inc, Canada
Horizon is an integrated, ultra-fast genomic intelligence platform designed to streamline and enhance precision oncology workflows. The software delivers end-to-end analytical capabilities spanning somatic and germline…
- Oral · In-Person
Reovirus inhibits tumor antigen presentation leading to impaired cytotoxic-T responses
Raghad Khaleafi · Technion-Israel Institute of Technology, Israel
Oncolytic viruses are an emerging class of cancer immunotherapies, with several agents approved for clinical use. Mammalian reovirus-based therapies are currently being evaluated in numerous clinical trials, commonly in…
- Oral · In-Person
Beyond cytoreduction: A nursing case report on clinical surveillance and evolving hematologic risks during cytarabine-induced cytoreduction for recurrent hyperleukocytosis in relapsed acute myeloid leukemia
Sheena Grace Diamante · University of the Philippines-Philippine General Hospital, Philippines
Background / Context Recurrent hyperleukocytosis in acute myeloid leukemia (AML) presents evolving risks requiring timely escalation and adaptive nursing surveillance. Cytoreduction may be followed by profound…
- Oral · In-Person
Targeting KRAS G12V mutation in pancreatic cancer with heterologous peptide vaccination
Aditi Kumthekar · Hannover Medical School (MHH), Germany
The incidence of pancreatic cancer related mortality is rising globally - predicted to become the second leading cause of cancer related deaths worldwide. KRAS is an initiating driver mutation in pancreatic ductal…
- Oral · In-Person
Fate, clonal evolution, and therapeutic vulnerabilities of BRCA1-deficient cells in early breast tumorigenesis
Tatum van Maanen · Netherlands Cancer Institute, Netherlands
Germline BRCA1 mutations represent the most common cause of hereditary breast cancer. BRCA1 is essential for homologous recombination–mediated DNA repair, and loss of heterozygosity (LOH) abrogates its function, driving…
- Oral · In-Person
Intratumoral B. fragilis and F. nucleatum orchestrate immunosuppression in colorectal cancer via an NF-κB-dependent microbiota-CAF-MDSC-Treg axis
Xun Zeng · Zhejiang University, China
Background: Interactions among intratumoral microbiota, immune cells, tumor and stromal components are critical to the progression of colorectal cancer (CRC), yet the mechanisms remain incompletely defined. Objective…
- Poster · In-Person
Folate receptor-targeted nanocarrier delivery of noscapinoids for breast cancer therapy
Eeshara Naik · Sambalpur University, India
Introduction: Breast cancer remains the most prevalent malignancy among women, accounting for ~6.9% of cancer-related deaths annually, affecting 1 in 100 women. The fear of needles and the adverse effects of the current…
- Poster · In-Person
Impact of normalization strategies on the diagnostic performance of salivary microRNAs for early detection of oral squamous cell carcinoma: A systematic review, diagnostic meta-analysis, and meta-regression
Jamal Khan · Khyber College of Dentistry, Pakistan
Salivary microRNAs (miRNAs) are promising non-invasive biomarkers for the early detection of oral squamous cell carcinoma (OSCC), but variability in normalization strategies limits their reproducibility and clinical…
- Poster · In-Person
Pancreatic adenocarcinoma masquerading as superior mesenteric artery vasculitis: A case report and review of related literature
Tyrone Clyde Saludez · University of the Philippines, Philippines
INTRODUCTION Medium-vessel vasculitis involving the visceral circulation is rare and most commonly attributed to systemic vasculitides such as polyarteritis nodosa, or in older patients, giant cell arteritis. Its…
Day 2
- Keynote · Virtual
Precision oncology, genetic testing and gene therapy
Rajvir Dahiya · University of California San Francisco, United States
Precision oncology uses molecular and clinical information to select the most effective therapies while minimizing unnecessary toxicity. Genetic testing identifies inherited cancer predispositions and tumor-specific…
- Keynote · Virtual
Graphene quantum dots: A new frontier for photodynamic therapy
Paulo Cesar De Morais · Catholic University of Brasilia, Brazil
Fluorine-decorated graphene quantum dots (F@GQDs) will be herein explored as a material platform for application in photodynamic therapy (PDT). GQDs have been extensively studied in biomedical areas such as bioimaging…
- Oral · Virtual
A novel mechanism of mitotic spindle formation in cancer cells
Eleni Petsalaki · University of Crete, Greece
During mitosis sister chromatids are accurately segregated into two daughter cells through a microtubule-based structure known as the mitotic spindle. Mitotic spindle assembly is a crucial machinery of cell…
- Oral · Virtual
Human papillomavirus prevalence and genotype distribution among cervical cancer susceptible women of North Indian ethnicity in Gardasil vaccination era: Public health impact
Saumya Pandey · Indira IVF Hospital, India
Objectives : Human papillomavirus (HPV) is the major etiological agent of cervical cancer, a leading cause of morbidity and mortality in women worldwide; screening strategies for reducing the burden of HPV-mediated…
- Oral · Virtual
Genome-wide identification of SOX7 downstream targets and pathways in multiple myeloma through ChIP-Seq and RNA-Seq
Can Küçük · Dokuz Eylul University, Turkey
Multiple myeloma (MM) is one of the most frequent hematological malignancies. The role of transcriptionally downregulated tumor suppressor genes has not been fully characterized in MM. As a transcription factor, SOX7…
- Oral · Virtual
Rehabilitation for cancer-related lymphedema: An evidence-based review of current interventions and clinical outcomes
Jagmohan Lal Meena · ACTREC - Tata Memorial Centre, India
Background: Cancer Related Lymphedema (CRL) is one of the most common long-term complications following cancer treatment, particularly among survivors of breast, gynaecological, genitourinary, head and neck, melanoma…
- Oral · Virtual
STAT proteins as regulators of epigenetic and epitranscriptomic landscapes in T helper cell differentiation in NSCLC
Koustav Sarkar · SRM Institute of Science and Technology, India
Non-small cell lung cancer (NSCLC) remains difficult to treat because nearly half of cases lack targetable mutations and often develop therapy resistance, making epigenetic reprogramming an attractive therapeutic…
- Oral · Virtual
Theranostic anti-glioma intelligent nanoplatform, CA and radiation sensitizer
MohammadNabil Savari · Islamic Azad University, Iran, Islamic Republic of
Glioblastoma multiforme (GBM) treatment poses significant challenges due to factors such as the blood-brain barrier (BBB), poor diagnostic capabilities at the cellular level, resistance to conventional therapies, and…
- Oral · Virtual
Investigation of anticancer agents using lithium and turmeric extract on the specific activity of β-galactosidase in glioblastoma (LN229) cell lines
Prabha Muddobalaiah · Ramaiah Institute of Technology, India
Background: Multiforme (GBM) are tumours arising from astrocytes, which are transformed, and the supportive cells of neurons. These tumours are highly malignant due to high proliferation capacity, angiogenesis…
- Oral · Virtual
MHC-based cancer immunotherapy
Saeid Abediankenari · Mazndaran university of medical sciences, Iran, Islamic Republic of
The Major Histocompatibility Complex (MHC) is a large group of glycoproteins, categorized into various types, which function to selectively bind peptide fragments. MHC class I molecules present cancer-associated peptide…
- Poster · Virtual
AI-guided optimization and structure-based virtual screening identify novel dual-state KRAS G12D inhibitor candidates
Mohamed Salaheldin Khattab · Suez Canal University, Egypt
Background: KRAS G12D is one of the most prevalent oncogenic drivers in pancreatic and colorectal cancers and remains a challenging therapeutic target because of its high affinity for GTP and the absence of a reactive…
Day 3
- Keynote · Virtual
Nanoparticle-based chemiluminescent detection of an ovarian cancer biomarker – A clinically-relevant pilot study
Michael Thompson · University of Toronto, Canada
Biomarker based detection for ovarian cancer (OC) in clinical settings is currently focused on the biomarker CA-125. This marker unfortunately has a fairly low sensitivity and specificity for ovarian cancer at only 82%…
- Keynote · Virtual
Evolving concepts of breast cancer management and recent trends
Manmohan Agrawal · Pushpadi Hospital, India
The prognosis of breast cancer remains unpredictable despite of frequent change in treatment protocol since last few decades. As we understand the heterogenous nature of the disease, complex tumor biology etc. the…
- Oral · Virtual
Investigating the role of mesenchymal stem cell exosomes programmed by the breast cancer microenvironment in the rearrangement of inflammatory pathways, phenotypic changes, and interaction with immune cells in a multicellular in vitro model
Ahora Chehri · Johann Wolfgang Goethe Universität Frankfurt am, Germany
Breast cancer is widely recognized as a biologically complex disease, in large part because of its continuous and dynamic interactions with the surrounding tumor microenvironment. Among the stromal elements, mesenchymal…
- Oral · Virtual
The mathematical interpretation of breast cancer drugs
Ratan Kumar Sarkar · Independent Researcher, India
The fundamental values in the system 87 + 250 = 337 = 338(i.e. 676/2) -1 where ‘1’ is about common in the system and 900 – 676 = 224 and 676 – 224 = 452 = 561 – 109 in structural complex. In pathways, 777(lunar time)…
Present your research at CIOC 2027
Abstract submissions for the 2027 program are open · March 15–17, 2027 · Village Hotel Changi, Singapore.
Join the CIOC 2027 delegation
Singapore · March 15–17, 2027· Hybrid · in-person & virtual
Attend without presenting.